Evidence map›Paper›PMID 40321805›Full record

ArticleInternational journal of nanomedicine2025

Carbon-Encapsulated Iron Nanoparticles Seeking Integrins in Murine Glioma.

Agnieszka Stawarska, Magdalena Bamburowicz-Klimkowska, Michał Bystrzejewski, Artur Kasprzak, Ireneusz P Grudzinski

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Agnieszka Stawarska *Department of Toxicology and Food Science, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.ORCID 0000-0001-9345-1254
Magdalena Bamburowicz-Klimkowska *Department of Toxicology and Food Science, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.ORCID 0000-0003-2213-415X
Michał BystrzejewskiDepartment of Physical Chemistry, Faculty of Chemistry, Warsaw University, Warsaw, Poland.
Artur KasprzakDepartment of Organic Chemistry, Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland.
Ireneusz P GrudzinskiDepartment of Toxicology and Food Science, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Targeting integrin receptors for MRI represents a novel method in diagnosing glioblastoma. In the present study carbon-encapsulated iron nanoparticles to explore murine glioma tracking based upon specific direct targeting with monoclonal antibodies against the beta-3 subunit (CD61) of the integrin αVβ3 receptor are described. Methods: The carbon arc discharge method was used to synthesize nanoparticles and amidation-type reaction were applied to attach monoclonal antibody (anti-CD61) with acidic group functionalized nanoparticles to lead two types of bioconjugates (Fe@C-CONH-anti-CD61 and Fe@C-(CH Results: The results showed that Fe@C-CONH-anti-CD61 and Fe@C-(CH Conclusion: The carbon-encapsulated iron nanoparticles functionalized with monoclonal antibodies recognizing the beta-3 subunit of the integrin αVβ3 receptor can be considered as a potential contrast agent for MRI-based tracking glioblastoma.

Indexed as

Brain NeoplasmsCarbonGliomaIntegrin alphaVbeta3IronAnimalsAntibodies, MonoclonalCell Line, TumorMagnetic Resonance ImagingMiceMice, Inbred C57BLAntibodies, MonoclonalCarbonIntegrin alphaVbeta3Ironcarbon-encapsulated iron nanoparticlescytotoxicityglioblastomaintegrinsmagnetic resonance imagingmonoclonal antibodies

Identifiers

PMID40321805
PMCPMC12048782

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.