Evidence map›Paper›PMID 40321736›Full record

ArticleHeart rhythm O22025

Post-pulmonary vein isolation voltage remapping-guided incremental lesions: A feasible strategy to improve long-term outcomes.

Juan F Rodriguez-Riascos, Hema Srikanth Vemulapalli, Padmapriya Muthu, Aria Raman, Poojan Prajapati, Shruti Iyengar, Sumedh Iyengar, Hicham El Masry, Arturo M Valverde, Komandoor Srivathsan

Abstract read
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Left atrial appendage occlusion in patients with end-stage renal disease: an individual patient-level meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Pooled it
  2. Observational
  3. Article
  4. The blanking interval after atrial fibrillation ablation: time for reassessment with pulsed field energy.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Juan F Rodriguez-RiascosDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.
Hema Srikanth VemulapalliDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.
Padmapriya MuthuDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.
Aria RamanDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.
Poojan PrajapatiDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.
Shruti IyengarDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.
Sumedh IyengarDepartment of Internal Medicine, Bridgeport Hospital, Yale New Haven Health, Bridgeport, Connecticut.
Hicham El MasryDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.
Arturo M ValverdeDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.
Komandoor SrivathsanDivision of Cardiovascular Diseases, Mayo Clinic Hospital, Phoenix, Arizona.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary vein isolation (PVI) has demonstrated acceptable success rates; however, there is still potential for improvement. Pulmonary reconnection remains the main problem and the role of adjunctive strategies, such as repeat mapping to guide additional lesions to enhance durability of pulmonary vein isolation, remains uncertain. Objective: This study aimed to evaluate the impact of post-PVI high-density remapping with guided incremental lesions on long-term recurrence-free survival. Methods: This study included consecutive patients who underwent PVI between 2015 and 2023. Patients were divided into 2 groups based on whether they received post-PVI high-density remapping. Those in the remapping group with documented areas of incomplete ablation received incremental lesions to achieve complete ablation. The primary endpoint was recurrence-free survival. Results: A total of 588 patients, with a mean follow-up of 25.8 months, were included. Post-PVI remapping was performed in 243 patients, while 345 patients underwent conventional PVI. Post-PVI remapping with guided incremental lesions improved recurrence-free survival compared with conventional PVI (adjusted hazard ratio 0.75, 95% confidence interval [CI] 0.57-0.99, Conclusion: Postablation mapping effectively identifies and addresses proarrhythmic foci, potentially reducing atrial fibrillation recurrence and improving patient outcomes.

Indexed as

Atrial fibrillationCatheter ablationCryoballoon catheter ablationPulmonary vein isolationRadiofrequency catheter ablationVoltage mapping

Identifiers

PMID40321736
PMCPMC12047520

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.