ArticleMayo Clinic proceedings. Innovations, quality & outcomes2025
Syncope and All-Cause Mortality in Heart Failure: A Propensity Score-Matched Analysis.
Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
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Abstract
Objective: To examine the association between syncope and all-cause mortality in a large cohort of patients with heart failure (HF) with syncope. Patients and Methods: We retrospectively identified a cohort of patients with HF and syncope from January 1, 2010, to December 31, 2015, and matched them in a 1:1 propensity analysis with patients with HF without syncope. A multivariable Cox regression model was used to estimate the association between syncope and the end point, all-cause mortality. Results: During the study period, 3449 patients with HF were diagnosed with syncope (mean ± SD age, 72.8±14.3 years). At 12 months follow-up, syncope was not an independent risk factor of all-cause mortality in overall patients with HF (hazard ratio [HR], 0.98; 95% CI, 0.91-1.04; Conclusion: Syncope was not an independent risk of all-cause mortality for patients with HF but significantly predicted the all-cause mortality in the subgroup of patients with heart failure reduced EF with cardiac implantable electronic devices.
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