Evidence map›Paper›PMID 40321706›Full record

ArticleJournal of global health economics and policy2025

Implementation science research to understand the readiness of a mobile clinic intervention to screen for high-risk HPV infections and associated morbidity in Mali and Nigeria.

Kate Klein, Imran Morhason-Bello, Lifang Hou, Mamoudou Maiga, Ibrahima Téguété, Caryn E Peterson

Abstract read
In one paragraph

Article in Journal of global health economics and policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kate KleinHavey Instititute for Global Health, Northwestern University.
Imran Morhason-BelloDepartment of Obstetrics and Gynecology, and HPV Consortium, College of Medicine, University of Ibadan.
Lifang HouDepartment of Preventive Medicine, Northwestern University.
Mamoudou MaigaDepartment of Preventative Medicine, Northwestern University.
Ibrahima TéguétéObstetrics and Gynocology, USTTB.
Caryn E PetersonSchool of Public Health, Division of Epidemiology and Biostatistics, Center for Global Health, University of Illinois Chicago.

Funding

Epigenetic study of oral HPV infection-associated oral cancer in people living with HIV in NigeriaR01CA274952 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOU, LIFANG, MORHASON - BELLO, IMRAN · 2022 to 2025
$3.3M
West Africa Self-Sampling HPV Based Cervical Cancer Control Program (WA-SS-HCCP) for WLWHA: Barriers, challenges, and needsU01CA275129 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JANE Louise HOLL, Lifang Hou · 2022 to 2026
$3.2M
Infection-Associated Cancer Research Training Program in MaliD43CA260658 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOU, LIFANG, MAIGA, MAMOUDOU · 2021 to 2025
$1.3M
Mali-Northwestern University Breast Cancer Prevention Research Training Program (MN-BCP)D43TW013008 · FIC · UNIV OF SCIENCES, TECH & TECH OF BAMAKO · PI BREHIMA DIAKITE, JANE Louise HOLL · 2025 to 2026
$496k
FIC NIH HHS D43 TW013008NCI NIH HHS D43 CA260658NCI NIH HHS R01 CA274952NCI NIH HHS U01 CA275129
6 · The paper itself

Abstract

Access to and community acceptance of point-of-care testing for high-risk human papillomavirus (hrHPV) are vital to cervical cancer (CC) prevention. The World Health Organization (WHO) reports high rates of HPV-16/18 (oncogenic hrHPV strains) in Sub-Saharan Africa (SSA). In rural Mali and peri-urban Nigeria, prevention efforts are limited by cognitive, socio-cultural, logistical, and resource-related barriers, leading to ongoing transmission, late diagnoses, limited treatment options, and preventable deaths. To address these barriers, we prepared a mobile clinic intervention providing self-sample collection and rapid hrHPV testing. Pre-implementation research assessed factors influencing success in both countries. Using implementation science methods, focus groups per target community were conducted with political/administrative, religious, business, community leaders, and women of screening age. Participants also completed a short survey on HPV knowledge. Data were analysed using descriptive statistics and thematic analysis. From January 2024 to January 2025, planning occurred alongside the mobile clinic's manufacturing and shipping. Eighteen focus groups were held between January and March 2025 - ten in Mali (with additional sessions for marketplace leaders) and eight in Nigeria. Results will inform site-specific adaptations. A follow-up study will document real-time implementation adjustments to support scale-up. Culturally tailored, context-specific strategies are key to addressing disparities in HPV-related cancer prevention. Implementation science can assess community readiness and guide effective intervention delivery.

Indexed as

Cervical CancerHPVHPV DNA testingLMICMobile ClinicSelf Sampling

Identifiers

PMID40321706
PMCPMC12048031

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.