Evidence map›Paper›PMID 40321516›Full record

ReviewACS omega2025

Strategies for Actinobacteria Isolation, Cultivation, and Metabolite Production that Are Biologically Important.

Samson Cheruiyot Koech, Michaela Plechatá, Wasu Pathom-Aree, Zdenek Kamenik, Amit Jaisi

Abstract readReview
In one paragraph

Review in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. International journal of systematic and evolutionary microbiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Isolation and characterization of endophytic actinobacteria associated with Artemisia judaica L. ssp. sahariensis from desert regions in Algeria.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samson Cheruiyot KoechSchool of Pharmacy, Walailak University, Thasala, Thai Buri, Nakhon Si Thammarat 80160, Thailand.
Michaela PlechatáInstitute of Microbiology, Czech Academy of Sciences, Videnska 1083, 14200 Prague, Czech Republic.ORCID https://orcid.org/0000-0001-5064-2026
Wasu Pathom-AreeDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID https://orcid.org/0000-0003-0299-3731
Zdenek KamenikInstitute of Microbiology, Czech Academy of Sciences, Videnska 1083, 14200 Prague, Czech Republic.
Amit JaisiSchool of Pharmacy, Walailak University, Thasala, Thai Buri, Nakhon Si Thammarat 80160, Thailand.ORCID https://orcid.org/0000-0003-0261-7170

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel antimicrobial agents are urgently needed to combat antimicrobial resistance from multidrug-resistant organisms. Actinobacteria are key sources of bioactive metabolites with diverse biological activities. Despite their contributions to drug discovery, the process from strain identification to drug manufacturing faces many challenges, especially the rediscovery of known compounds. Recent technological and scientific advancements have accelerated drug development. Efforts to isolate and screen rare actinobacterial species could yield novel bioactive compounds. This review summarizes techniques for selectively isolating rare actinobacteria, improving bioactive metabolite production, and discovering potential strains. Notably, new genomic strategies and new discoveries regarding spectroscopic signature-based bioactive natural products containing specific structural motifs are also discussed. Furthermore, this review updates the compounds derived from rare actinobacteria and their biological applications.

Identifiers

PMID40321516
PMCPMC12044489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.