ArticlemedRxiv : the preprint server for health sciences2025
Modeling the impact of case finding for tuberculosis: The role of infection dynamics.
Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Population-level case-finding is globally recommended as a strategy to reduce the burden of tuberculosis in high-burden settings, but mathematical models overwhelmingly project that case-finding will yield only modest reductions in incidence. We evaluated whether the common assumption of lifelong risk of progression after infection leads models to undervalue the impact of case-finding. Specifically, clearance of latent infection reduces the rate of long-term "reactivation", which could result in more pronounced effects from interventions (such as case-finding) that reduce
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