ArticleClinical case reports2025
Constrictive Pericarditis as a Rare Manifestation of Graft-Versus-Host Disease: A Case Report.
Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Graft-versus-host disease (GVHD) is a serious inflammatory complication that can arise after allogeneic transplantation, characterized by donor T-cells attacking the recipient's tissues. While cardiac complications are infrequent, they are more commonly observed in cases of chronic GVHD and may manifest as pericardial effusion, cardiac tamponade, and various arrhythmias. Additionally, chronic GVHD can result in constrictive pericarditis (CP) due to the accumulation of fluid and scarring. A 25-year-old Iranian man developed CP 14 years after undergoing allogenic stem cell transplantation. Following inadequate response to medical therapy, he underwent a pericardiectomy. Pathological examination during follow-up revealed fibrosis and mild chronic inflammation. This report aims to add another case of cardiac manifestation associated with GVHD to the current literature. The main message emphasizes the urgent need for prompt diagnosis and effective pericardiectomy, which can be life-saving. Surgical referral should always be an option, and post-operative immunomodulation is crucial.
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