ArticlebioRxiv : the preprint server for biology2025
Neuronal titration of
Rachel J Boyd, A Ra Kho, Sarah A McClymont, Stacie K Loftus, Han Seok Ko, Andrew S McCallion
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors.
Rachel J BoydMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-6544-8541 A Ra KhoNeuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Sarah A McClymontMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Stacie K LoftusGenetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Han Seok KoNeuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Andrew S McCallionMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-0016-8466 Funding
Predoctoral Training Program in Human GeneticsT32GM007814 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VALLE, DAVID · 1985 to 2021
$10.6MSystematic investigation of disease-associated, regulatory variation; illuminating their prediction, molecular consequences and mechanisms contributing to risk of Parkinson disease (PD)R01NS134805 · NINDS · JOHNS HOPKINS UNIVERSITY · PI ANDREW S MCCALLION · 2024 to 2026
$1.9MThe role of NOD2/RIPK2 signaling in the pathogenesis of Parkinson's DiseaseR01NS107404 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KO, HANSEOK · 2018 to 2022
$1.8MDetermination of the clinical relevance of Parkinson disease-associated intronic enhancer of the alpha-synuclein gene, in a novel mouse deletion modelR21NS128604 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KO, HANSEOK, MCCALLION, ANDREW S · 2023 to 2024
$450kValidation of Small Molecule Enhancers of Mutant Glucocerebrosidase 1 ActivityR03NS135450 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KO, HANSEOK · 2024 to 2024
$164kNIGMS NIH HHS T32 GM007814NINDS NIH HHS R01 NS107404NINDS NIH HHS R01 NS134805NINDS NIH HHS R03 NS135450NINDS NIH HHS R21 NS128604
6 · The paper itselfAbstract
Indexed as
enhancergene regulationmouse modelParkinson’s diseasepre-formed fibrilsα-synuclein
Identifiers
PMID40321202
PMCPMC12047861
What OpenQuestion holds
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