Evidence map›Paper›PMID 40321157›Full record

ArticleOpen life sciences2025

Rong Huang, Xi Yong, Tingting Li, Huling Wen, Xing Zhou, Yichen Liao, Jun You, Chunlei Yu, Peng Xu, Yuquan Wang and 9 more

Abstract read
In one paragraph

Article in Open life sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Research (Washington, D.C.) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Rong HuangInstitute of Materia Medica, School of Pharmacy, North Sichuan Medical College, No. 234, Fujiang Road, Nanchong, Sichuan, 637000, China.
Xi YongDepartment of Vascular Surgery, Department of Nuclear Medicine, Radiotherapy Department, Department of Oncology, Department of Pharmacy, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Tingting LiDepartment of Pharmacy, Second Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Huling WenDepartment of Vascular Surgery, Department of Nuclear Medicine, Radiotherapy Department, Department of Oncology, Department of Pharmacy, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Xing ZhouTranslational Medicine Research Center, Institute of Hepatobiliary Research, School of Basic Medical Sciences, North Sichuan Medical College, Nanchong, Sichuan, China.
Yichen LiaoInstitute of Materia Medica, School of Pharmacy, North Sichuan Medical College, No. 234, Fujiang Road, Nanchong, Sichuan, 637000, China.
Jun YouInstitute of Materia Medica, School of Pharmacy, North Sichuan Medical College, No. 234, Fujiang Road, Nanchong, Sichuan, 637000, China.
Chunlei YuInstitute of Materia Medica, School of Pharmacy, North Sichuan Medical College, No. 234, Fujiang Road, Nanchong, Sichuan, 637000, China.
Peng XuDepartment of Vascular Surgery, Department of Nuclear Medicine, Radiotherapy Department, Department of Oncology, Department of Pharmacy, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Yuquan WangDepartment of Vascular Surgery, Department of Nuclear Medicine, Radiotherapy Department, Department of Oncology, Department of Pharmacy, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Dan WenDepartment of Vascular Surgery, Department of Nuclear Medicine, Radiotherapy Department, Department of Oncology, Department of Pharmacy, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Tianqin XiaInstitute of Materia Medica, School of Pharmacy, North Sichuan Medical College, No. 234, Fujiang Road, Nanchong, Sichuan, 637000, China.
Hao YangTranslational Medicine Research Center, Institute of Hepatobiliary Research, School of Basic Medical Sciences, North Sichuan Medical College, Nanchong, Sichuan, China.
Yanqin ChenTranslational Medicine Research Center, Institute of Hepatobiliary Research, School of Basic Medical Sciences, North Sichuan Medical College, Nanchong, Sichuan, China.
Lei XuTranslational Medicine Research Center, Institute of Hepatobiliary Research, School of Basic Medical Sciences, North Sichuan Medical College, Nanchong, Sichuan, China.
Xiaorong ZhongTranslational Medicine Research Center, Institute of Hepatobiliary Research, School of Basic Medical Sciences, North Sichuan Medical College, Nanchong, Sichuan, China.
Xianfu LiDepartment of Vascular Surgery, Department of Nuclear Medicine, Radiotherapy Department, Department of Oncology, Department of Pharmacy, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Zhengmin XuInstitute of Materia Medica, School of Pharmacy, North Sichuan Medical College, No. 234, Fujiang Road, Nanchong, Sichuan, 637000, China.
Chunyang ZhouInstitute of Materia Medica, School of Pharmacy, North Sichuan Medical College, No. 234, Fujiang Road, Nanchong, Sichuan, 637000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

15-Lipoxygenase-2 (15-Lox-2) is one of the key enzymes in arachidonic acid (AA) metabolic pathway, which belongs to the unsaturated fatty acid metabolic pathway. This pathway is involved in the foam cell transformation of macrophages during the progression of atherosclerosis (AS). The role of salidroside (SAL) in cardiovascular diseases has been extensively studied, but its impact on macrophage foam cell formation has not yet been clearly clarified. We aimed to determine the effects of

Indexed as

15-lipoxygenase-2arachidonic acidfoam cell formationmacrophagessalidroside

Identifiers

PMID40321157
PMCPMC12048898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.