ReviewThe Journal of infectious diseases2025
The Impact of Diet on Clostridioides difficile Infection: A Review.
Review in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- The Bile Acid-Diet-Microbiome Axis inNutrients · 2026Review
- Repurposing azole antifungals as rapid bactericidal, membrane-disruptive therapeutics againstMicrobiology spectrum · 2026Article
- Review
- Article
- Dietary Quality and Microbiome Profiles among Rectal Cancer Patients: A Cross-Sectional Pilot Study.Puerto Rico health sciences journal · 2026Article
- Diet-Microbiome Analysis in a Healthy Cohort Reveals Potential Role of Intestinal Microbiota in Metabolism.bioRxiv : the preprint server for biology · 2026Article
- High-fat diet rewires gut host-microbiota relationship to derive worse outcomes followingbioRxiv : the preprint server for biology · 2026Article
- Non-targeted metabolomics reveals metabolic signatures associated withFrontiers in microbiology · 2026Article
- The Ambivalent Nature ofToxins · 2025Review
- The exploitation of nutrient metals by bacteria for survival and infection in the gut.PLoS pathogens · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Clostridioides difficile poses a significant public health challenge as it is the leading cause of antibiotic-associated diarrhea and is associated with significant morbidity and mortality. Clostridioides difficile's metabolism and pathogenesis are strongly influenced by nutrient availability from the host and gut commensals. This has caused increasing interest in dietary intake and diet-derived metabolites' role in C difficile infection (CDI). Although much of the data currently originates from animal models, there is growing evidence of the ability of diet to impact CDI-related outcomes. This review aims to enrich the understanding of dietary components that impact C difficile metabolism and pathogenesis, as well as provide limitations in the current science to support future inquiry. Without a better understanding of the influence of diet on CDI in the human host, we lack a nonpharmacologic approach to prevent and treat this important condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.