SynthesisInternational wound journal2025
Risk factors for surgical site infections after orthopaedic surgery: A meta-analysis and systematic review.
Synthesis in International wound journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Assessment of risk factors for surgical site infection following tibial plateau levelling osteotomy: a systematic review and meta-analysis.The Journal of small animal practice · 2026Pooled it
- Risk factors for surgical site infections after orthopaedic surgery: A meta-analysis and systematic review.International wound journal · 2025Pooled it
- Harnessing gasotransmitters for orthopaedic infection therapy: Mechanisms and advanced delivery platforms.Bioactive materials · 2027Review
- Zero confirmed allergic reactions to cefazolin in an elective orthopedic cohort with high prevalence of reported beta-lactam allergies.JSES reviews, reports, and techniques · 2026Article
- [Perioperative antibiotic prophylaxis in trauma surgery and orthopedics].Unfallchirurgie (Heidelberg, Germany) · 2026Article
- Full-Body Versus Local Wipe Disinfection With Chlorhexidine Gluconate: No Difference in Surgical Site Infection After Acute Hip Fracture Surgery.International wound journal · 2026Article
- Distribution of putative SSI risk factors in adults undergoing open reduction and fixation of long bone fracture.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Observational
- Article
- Efficiency of NSAIDs in preventing prosthetic joint infections (PJIs): inhibition of Staphylococcus aureus biofilms by etoricoxib through down regulation of bacterial adhesion genes.Archives of microbiology · 2026Article
- Impact of cannabis use and tobacco smoking on outcomes of open carpal tunnel release surgery: a nationwide study in the United States.Archives of orthopaedic and trauma surgery · 2026Article
- Time-dependent microbial colonisation of temporary external fixations: a prospective descriptive study.Journal of orthopaedic surgery and research · 2026Article
- Body mass index, not local adiposity, best predicts surgical site infection following surgical fixation of distal femur fractures.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Prevention and Treatment of Surgical Site Infections in Orthopaedic Surgery: An Italian Delphi Consensus on Risk Stratification and Wound Irrigation Strategies.Journal of clinical medicine · 2026Review
- Perioperative Management of Biologic and Targeted Synthetic DMARDs in Orthopedic Surgery: Balancing Infection Risk and Disease Control.Microorganisms · 2026Review
- Perioperative nursing process-oriented bundled interventions and digital monitoring for the prevention of surgical site infections.Frontiers in medicine · 2026Review
- Predictive value of a preoperative computed tomography-derived perifracture soft-tissue envelope index for fracture-related infection after open reduction and internal fixation of tibial plateau fractures.Frontiers in medicine · 2026Article
- Diabetes mellitus is an independent risk factor for surgical site infection after orthopedic Class I incision surgery: a retrospective cohort study.Frontiers in surgery · 2026Article
- BMI-stratified nomograms to predict early SIRS-defined sepsis after flexible ureteroscopy.Frontiers in medicine · 2026Article
- The Threshold Fallacy: Cutting the Evidence to Fit the Bed.International wound journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this meta-analysis was to investigate the occurrence and determinants of surgical site infections (SSIs) in individuals following orthopaedic surgical procedures. A systematic exploration of articles concerning factors predisposing individuals to SSIs after orthopaedic surgery was conducted across multiple databases, including PubMed, Embase, Cochrane Library and Web of Science, up to March 20, 2024. The Stata 15.0 software was employed to estimate combined odds ratios (ORs) utilizing either a random-effects model or a fixed-effects model based on the degree of heterogeneity among the included studies. Egger's test was used to assess publication bias. Among the 1248 records retrieved, 45 articles were deemed eligible after screening for studies incorporating multivariate analyses of risk factors associated with SSIs. These comprised four case-control studies and 41 cohort studies, collectively involving 1 572 160 patients, among whom 43 971 cases of SSIs were reported postoperatively. Meta-analysis outcomes indicated significant associations between SSIs and the following factors: low Albumin levels (<35 g/L; OR = 2.29, 95% confidence interval [CI]: 1.45-3.62, p = 0.0001), ASA score >2 (OR = 2.32, 95% CI: 1.86-2.89, p = 0.0001), elevated body mass index (BMI) (>24 kg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.