ArticleClinical endocrinology2025
Management of Maternal Hypothyroidism in Pregnancy: A Danish Regional Study.
Article in Clinical endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectiveHypothyroidism in pregnant women must be carefully managed to prevent complications. The aim of this study was to evaluate compliance with clinical recommendations for the monitoring and treatment of hypothyroidism in pregnant women and to assess the clinical action upon each biochemical monitoring at different time points in pregnancy.
designRetrospective cohort study.
participantsPregnant women with known hypothyroidism in the North Denmark Region, 2022-2024, who were managed in the Departments of Endocrinology. MEASUREMENTS: Medical records were reviewed for information on biochemical monitoring of thyroid-stimulating hormone (TSH) and Levothyroxine (L-T4) treatment in the pregnancy. The primary study endpoint was the frequency of biochemical monitoring and dose adjustments of L-T4.
resultsAltogether 175 pregnant women with hypothyroidism treated with L-T4 before the pregnancy were studied. Biochemical monitoring of TSH in the pregnancy was performed one to 12 times (median 7 times). When considered until and including the 12th week of pregnancy, the number of women with dose adjustment following biochemical control was 84 of 166 (50.6% (95% CI: 42.7%-58.4%)), whereas from the 13th to 24th week it was 35 of 164 (21.3% (95% CI: 15.3%-28.4%)), and from the 25th week of pregnancy and onwards it was 17 of 165 (10.3% (95% CI: 6.1%-16.0%)).
conclusionIn a Danish regional cohort of pregnant women with hypothyroidism, biochemical monitoring of thyroid function was often performed and was mostly followed by a change in the dose of L-T4 in early pregnancy ( ~ 50% of the women) and rarely in late pregnancy ( ~ 10% of the women).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.