Evidence map›Paper›PMID 40320438›Full record

ArticleScientific reports2025

Enhancing lung cancer detection through integrated deep learning and transformer models.

Revathi Durgam, Bharathi Panduri, V Balaji, Adil O Khadidos, Alaa O Khadidos, Shitharth Selvarajan

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Swallow Winged Kite Optimization with Shuffle Attention Xtreme Gradient Boost Network for lung cancer detection using CT image.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Artificial intelligence in respiratory medicine: From diagnosis to treatment and future directions.Chinese medical journal pulmonary and critical care medicine · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Revathi DurgamDepartment of Data Science, AVN Institute of Engineering and Technology, Hyderabad, India.
Bharathi PanduriDepartment of Information Technology, Gokaraju Rangaraju Institute of Engineering & Technology, Hyderabad, India.
V BalajiDepartment of CSE-AIML, Vardhaman College of Engineering, Hyderabad, India.
Adil O KhadidosDepartment of Information Technology, Faculty of Computing and Information Technology, King Abdulaziz University, Jeddah, Saudi Arabia.
Alaa O KhadidosDepartment of Information Systems, Faculty of Computing and Information Technology, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Shitharth SelvarajanDepartment of Computer Science and Engineering, Kebri Dehar University, Kebri Dehar, Ethiopia. shitharths@kdu.edu.et.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer has been stated as one of the prevalent killers of cancer up to this present time and this clearly underlines the rationale for early diagnosis to enhance life expectancy of patients afflicted with the condition. The reasons behind the usage of the transformer and deep learning classifiers for the detection of lung cancer include accuracy, robustness along with the capability to handle and evaluate large data sets and much more. Such models can be more complex and can help to utilize multiple modalities of data to give extensive information that will be critical in ascertaining the right diagnosis at the right time. However, the existing works encounter several limitations including reliance on large annotated data, overfitting, high computation complexity, and interpretability. Third, the issue of the stability of these models' performance when applied to actual clinical datasets is still an open question; this is an even bigger issue that will greatly reduce the actual utilization of these models in clinical practice. To tackle these, we develop a novel Cancer Nexus Synergy (CanNS), which applies of A. Swin-Transformer UNet (SwiNet) Model for segmentation, Xception-LSTM GAN (XLG) CancerNet for classification, and Devilish Levy Optimization (DevLO) for fine-tuning parameters. This paper breaks new ground in that the presented elements are incorporated in a manner that co-operatively elevates the diagnostic capabilities while at the same time being computationally light and resilient. These are SwiNet for segmented analysis, XLG CancerNet for precise classification of the cases, and DevLO that optimizes the parameters of the lung cancer detection system, making the system more sensible and efficient. The performance outcomes indicate that the CanNS framework enhances the detection's accuracy, sensitivity, and specificity compared to the previous approaches.

Indexed as

Deep LearningEarly Detection of CancerLung NeoplasmsAlgorithmsHumansAnd classificationDeep learningDisease detectionLung CancerOptimizationSegmentationTransformer models

Identifiers

PMID40320438
PMCPMC12050323

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.