Evidence map›Paper›PMID 40320368›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2025

Impacts of Chalcogen Bonding on the Stability and Reactivity of 5-Iminothianthrene Platform: Toward Electrophilic Nitrogen Sources.

Ryutaro Tawara, Shohei Hamada, Takumi Furuta, Yusuke Kobayashi

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryutaro TawaraDepartment of Pharmaceutical Chemistry, Kyoto Pharmaceutical University, 1 Misasagishichono-cho, Yamashina-ku, Kyoto, 607-8412, Japan.
Shohei HamadaDivision of Pharmaceutical Sciences, Graduate School of Medical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.
Takumi FurutaDepartment of Pharmaceutical Chemistry, Kyoto Pharmaceutical University, 1 Misasagishichono-cho, Yamashina-ku, Kyoto, 607-8412, Japan.
Yusuke KobayashiDepartment of Pharmaceutical Chemistry, Kyoto Pharmaceutical University, 1 Misasagishichono-cho, Yamashina-ku, Kyoto, 607-8412, Japan.ORCID https://orcid.org/0000-0003-3074-7378

Funding

JSPS KAKENHI 23K24011JSPS KAKENHI 24K02158
6 · The paper itself

Abstract

The thianthrene scaffold has recently attracted significant attention in various coupling reactions. Although 5-iminothianthrene and its derivatives are expected to function as electrophilic aminating reagents, their properties and reactivity have not been fully investigated. In this work, it was found that 5-iminothianthrene reacted with various electrophiles, such as acid chlorides, protons, and isothiocyanates to give the corresponding adducts. In addition, intramolecular chalcogen bonding (ChB) was identified in those adducts, and this interaction was found to contribute to their stability and reactivity. Finally, the potential of N-acyliminothianthrenes as N-acylnitrene equivalents was demonstrated.

Indexed as

cyanamidemetathesisnitrenenoncovalent interactionsphoto‐irradiation

Identifiers

PMID40320368
PMCPMC12160997

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.