Evidence map›Paper›PMID 40319888›Full record

ArticleAmerican journal of nephrology2025

Sociodemographic Barriers to Starting the Kidney Transplantation Evaluation Process and Waitlisting in the Ohio River Valley.

Catherine E Kelty, Jade Buford, Kelsey M Drewry, Oluwafisayo Adebiyi, Asif Sharfuddin, Jonathan A Fridell, Syed Jawad Sher, Anne M Huml, Adam S Wilk, Stephen O Pastan and 2 more

Abstract read
In one paragraph

Article in American journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Catherine E KeltyDivision of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jade BufordRegenstrief Institute, Indianapolis, Indiana, USA.
Kelsey M DrewryRegenstrief Institute, Indianapolis, Indiana, USA.
Oluwafisayo AdebiyiDivision of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Asif SharfuddinDivision of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jonathan A FridellDepartment of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Syed Jawad SherDivision of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Anne M HumlDepartment of Kidney Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Adam S WilkRegenstrief Institute, Indianapolis, Indiana, USA.
Stephen O PastanRenal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Sharon M MoeDivision of Nephrology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Rachel E PatzerRegenstrief Institute, Indianapolis, Indiana, USA, rapatzer@iu.edu.

Funding

Improving Quality and Access to Early Steps in Kidney TransplantationR01DK122701 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI PASTAN, STEPHEN, PATZER, RACHEL E · 2019 to 2022
$2.5M
Indiana University Kidney Training Program (IU-KTP)T32DK120524 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M · 2019 to 2023
$1.3M
NIDDK NIH HHS R01 DK122701NIDDK NIH HHS T32 DK120524
6 · The paper itself

Abstract

introductionIndividuals with end-stage kidney disease face barriers and delays in access to kidney transplantation, but little is known about access before waitlisting due to the lack of national data on pre-waitlisting measures. The Early Steps to Transplant Access Registry (E-STAR) captures referral and evaluation data in four US regions, including the Ohio River Valley, and this study utilizes E-STAR data to describe sociodemographic factors associated with starting the transplant evaluation and waitlisting in this region.

methodsAdults referred to a transplant center for evaluation within the Ohio River Valley during 2015-2021 and captured within E-STAR were included. Linked E-STAR, US Renal Data System, and American Community Survey data were used to assess the association between sociodemographic (age, sex, race or ethnicity, insurance status), clinical, and neighborhood factors and time from referral to evaluation start and time from evaluation start to waitlisting by Cox proportional hazards analyses.

resultsAmong 15,673 referred adults, the mean age was 55 years, and the majority were male (61.4%) and had public insurance (56.6%), while 21.3% were preemptively referred. Compared to individuals aged 18-29, all other age groups had a lower likelihood of starting the evaluation in the adjusted model. Black adults (vs. White; adjusted hazard ratio: 0.89 [95% CI: 0.81-0.98]), and those with Medicaid or Medicare were less likely to start the evaluation (vs. employer-sponsored, 0.58 [0.50-0.66]; 0.66 [0.66-0.82], respectively). Among individuals who started the evaluation, those with Black (vs. White) race, and Medicaid or Medicare (vs. employer-sponsored) were less likely to be waitlisted in the adjusted analysis.

conclusionAssociations between age, sex, race, and economic characteristics and access to evaluation start and waitlisting were observed. Future research investigating underlying causes and points of intervention in this region is warranted.

Indexed as

Health Services AccessibilityKidney Failure, ChronicKidney TransplantationWaiting ListsAdultAgedFemaleHumansMaleMedicaidMiddle AgedOhioReferral and ConsultationRegistriesSociodemographic FactorsSocioeconomic FactorsHealth equityKidney transplantationSocial disparities

Identifiers

PMID40319888
PMCPMC12306688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.