Evidence map›Paper›PMID 40319303›Full record

Observational studyAIDS research and therapy2025

Effectiveness of dolutegravir-based treatment among HIV/AIDS patients in Nkembo Outpatient Treatment Center, Gabon.

Christian Mangala, Rolf Moukanda-Ifoundou, Denis Maulot-Bangola, Alain Moutsinga, Christian Mombo-Maganga, Serge Christian Okolongo-Mayani, Brice Ongali, Guy Joseph Lemamy, Rachyda Massolou-Outata

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in AIDS research and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christian MangalaCatholic University of Central Africa, Yaoundé, Cameroon. imohu2004@yahoo.fr.ORCID 0000-0002-8367-5497
Rolf Moukanda-IfoundouOutpatient Treatment Center of Nkembo, Libreville, Gabon.
Denis Maulot-BangolaCatholic University of Central Africa, Yaoundé, Cameroon.
Alain MoutsingaCatholic University of Central Africa, Yaoundé, Cameroon.
Christian Mombo-MagangaNational Public Health Laboratory (NPHL), Libreville, Gabon.
Serge Christian Okolongo-MayaniCatholic University of Central Africa, Yaoundé, Cameroon.
Brice OngaliInternational Institute for Biomedical Research and Biotechnology Carles Kambangoye, Libreville, Gabon.
Guy Joseph LemamyUniversity of Health Sciences, Libreville, Gabon.
Rachyda Massolou-OutataOutpatient Treatment Center of Nkembo, Libreville, Gabon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHIV/AIDS therapy continues to make an enormous contribution to improving the well-being of HIV/AIDS patients globally. In Gabon, dolutegravir is administered to HIV/AIDS patients from first-line treatment. This study aimed to determine the effectiveness rate of dolutegravir-based treatment among HIV/AIDS patients.

methodsA retrospective observational study was conducted among HIV/AIDS patients who started antiretroviral treatment since 48 weeks of follow-up.

resultsThe effectiveness rate of dolutegravir-based treatment was 85.1%. HIV/AIDS patients with a CD4 + count below 200 cel/mm

conclusionDolutegravir-based treatment remains effective among HIV/AIDS patients treated at the Nkembo Outpatient Treatment Center.

Indexed as

Acquired Immunodeficiency SyndromeAnti-HIV AgentsHeterocyclic Compounds, 3-RingHIV InfectionsHIV Integrase InhibitorsAdultAmbulatory Care FacilitiesCD4 Lymphocyte CountDolutegravirFemaleGabonHumansMaleMiddle AgedOutpatientsOxazinesAnti-HIV AgentsDolutegravirHeterocyclic Compounds, 3-RingHIV Integrase InhibitorsOxazinesPiperazinesPyridonesDolutegravirGabonHIV/AIDS patientsTreatment effectiveness

Identifiers

PMID40319303
PMCPMC12049801

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.