Evidence map›Paper›PMID 40319277›Full record

Trial reportRespiratory research2025

Effect of periodontal therapy on lung function: a twelve-month follow-up intervention study.

Anders Røsland, Randi J Bertelsen, Joachim Heinrich, Stein Atle Lie, Andrei Malinovschi, Dagmar F Bunæs

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Respiratory research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04781153 (The Impact of Oral Bacteria on Lung Function and Inflammation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04781153 nacompletednot on this map

The Impact of Oral Bacteria on Lung Function and Inflammation

TypeinterventionalSponsorAnders RøslandRan2021 to 2024Enrolled62ConditionsPeriodontitis, Airway Obstruction, Lung InflammationArmsPeriodontal treatment
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anders RøslandDepartment of Clinical Dentistry, Section of Periodontics, University Of Bergen, Bergen, Norway. anders.rosland@uib.no.
Randi J BertelsenDepartment of Clinical Science, University Of Bergen, Bergen, Norway.
Joachim HeinrichInstitute of Occupational, Social, and Environmental Medicine, University of Munich (LMU), Munich, Germany.
Stein Atle LieDepartment of Clinical Dentistry, Centre for Translational Oral Research (TOR), University of Bergen, Bergen, Norway.
Andrei MalinovschiDepartment of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
Dagmar F BunæsDepartment of Clinical Dentistry, Section of Periodontics, University Of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence suggest an inflammatory link between respiratory health and periodontitis. This study aims to evaluate the impact of periodontal therapy on lung function.

methodsSixty-two never-smoking patients with mild periodontitis and without other medical conditions participated in this single-blind, prospective trial. Patients underwent periodontal therapy following an infection control approach. Lung function was measured using forced oscillation technique, assessing airway resistance and reactance, and spirometry evaluating FEV

resultsPatients (mean age 36 years, 58% female) showed significant improvements in periodontal parameters (p < 0.001). Oscillometry revealed a significant decrease in airway resistance at 11 Hz and 19 Hz after six weeks, with further significant decreases throughout the study. Resistance at 5 Hz (R

conclusionA decrease in airway resistance was observed after periodontal therapy, underscoring its positive impact on small airway function. These findings suggest that oral infection control is valuable for respiratory health in young adults before chronic conditions establish. CLINICAL

trial registrationThe trial was registered at ClinicalTrials.gov (NCT04781153) on February 19, 2021, prior to participant enrolment.

Indexed as

LungPeriodontitisAdultAirway ResistanceFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesRespiratory Function TestsSingle-Blind MethodSpirometryTreatment OutcomeYoung AdultLung function testingOral healthPeriodontitisRespiratory healthSmall airway resistance

Identifiers

PMID40319277
PMCPMC12049769

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.