Evidence map›Paper›PMID 40319257›Full record

Observational studyBMC primary care2025

A case scenario study on adherence to GINA recommendations by primary care physicians in an area of Southern Italy: the "Progetto Padre 2.0".

Mauro Maniscalco, Claudio Candia, Marta Coppola, Silvestro Ennio D'Anna, Carmen Lombardi, Claudia Merola, Antonio Iovine, Pasquale Ambrosino, Antonio Molino, Salvatore Fuschillo

Abstract readObservational Study
In one paragraph

Observational study in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mauro ManiscalcoPulmonary Rehabilitation Unit of Telese Terme Institute, Istituti Clinici Scientifici Maugeri IRCCS, Telese Terme, 82037, Italy. mauro.maniscalco@icsmaugeri.it.ORCID 0000-0001-6751-9921
Claudio CandiaPulmonary Rehabilitation Unit of Telese Terme Institute, Istituti Clinici Scientifici Maugeri IRCCS, Telese Terme, 82037, Italy.ORCID 0000-0002-5888-8781
Marta CoppolaDepartment of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, 80131, Italy.
Silvestro Ennio D'AnnaPulmonary Rehabilitation Unit of Telese Terme Institute, Istituti Clinici Scientifici Maugeri IRCCS, Telese Terme, 82037, Italy.
Carmen LombardiPulmonary Rehabilitation Unit of Telese Terme Institute, Istituti Clinici Scientifici Maugeri IRCCS, Telese Terme, 82037, Italy.
Claudia MerolaPulmonary Rehabilitation Unit of Telese Terme Institute, Istituti Clinici Scientifici Maugeri IRCCS, Telese Terme, 82037, Italy.
Antonio IovinePulmonary Rehabilitation Unit of Telese Terme Institute, Istituti Clinici Scientifici Maugeri IRCCS, Telese Terme, 82037, Italy.
Pasquale AmbrosinoIstituti Clinici Scientifici Maugeri IRCCS, Scientific Directorate of Telese Terme Institute, Telese Terme, 82037, Italy.
Antonio MolinoDepartment of Clinical Medicine and Surgery, University of Naples "Federico II", Naples, 80131, Italy.
Salvatore FuschilloPulmonary Rehabilitation Unit of Telese Terme Institute, Istituti Clinici Scientifici Maugeri IRCCS, Telese Terme, 82037, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate diagnosis and management of bronchial asthma are complex processes guided by national and international asthma guidelines, particularly the Global Initiative for Asthma (GINA). However, adherence to these guidelines is often suboptimal, varying across healthcare professionals and countries, which can lead to poor asthma control and increased healthcare costs.

aimIn this observational study, we assessed the alignment to GINA recommendations in the diagnosis and management of asthma among 15 primary care physicians in two metropolitan areas of the Campania region, Southern Italy.

methods120 patients were randomly selected from the electronic medical records of 15 primary care physicians. Afterwards, the alignment of diagnostic pathways and treatments with current GINA recommendations was assessed by an experienced chest physician. Three main outcomes were defined: diagnostic congruence, diagnostic workup congruence, and therapeutic congruence.

resultsOverall, 26.7% of our sample presented with an incongruous asthma diagnosis, while only 46.7% patients had therapeutic prescriptions in line with the latest GINA document recommendations. Patients treated in accordance with GINA recommendations exhibited significantly higher ACT scores, averaging 20.5 ± 4.0, compared to those receiving non-guideline-directed therapy, who averaged 15.7 ± 6.1 (p < 0.001). Diagnostic congruence showed a direct correlation with atopy (r = 0.277, p = 0.002) and an inverse correlation with ACT score (r = -0.335, p < 0.001).

conclusionsThe results of this study indicate that adherence to asthma guidelines in the metropolitan areas of Naples and Benevento remains insufficient. Further research focused on developing individualized interventions to manage non-adherence is warranted.

Indexed as

AsthmaGuideline AdherencePhysicians, Primary CarePractice Patterns, Physicians'AdultAgedFemaleHumansItalyMaleMiddle AgedPractice Guidelines as TopicAsthmaChronicityDisabilityGuidelinesOutcomeTherapy

Identifiers

PMID40319257
PMCPMC12049794

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.