Evidence map›Paper›PMID 40319157›Full record

ArticleScientific reports2025

Growing up in poverty, growing old in frailty: the life course shaping of health in the United States, England and Europe-a prospective and retrospective study.

Gindo Tampubolon

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gindo TampubolonUK NIHR Policy Research Unit on Healthy Ageing, Manchester, UK. tampubolon@manchester.ac.uk.ORCID https://orcid.org/0000-0002-9081-2349

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Project-001R01AG017644 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI Andrew Steptoe · 2000 to 2026
$56.2M
Enhancing the Comparability of SHARE with HRS and ELSAR01AG052527 · NIA · MAX PLANCK INST/SOCIAL LAW/SOCIAL POLICY · PI BOERSCH-SUPAN, AXEL H · 2016 to 2020
$2.1M
NIA NIH HHS R01 AG017644NIA NIH HHS R01 AG052527NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

Childhood poverty is directly associated with many health outcomes in late life irrespective of youth health and of health system variation. The childhood poor in the United States (U.S.), England and Europe have reported worse cognitive, muscle and mental functions in their fifties to nineties. But it is not known whether they have higher probabilities of experiencing frailty as their childhood recollections are likely to be erroneous. Nearly 80,000 adults aged 50 and older retrospectively recalled their childhood conditions around ten and underwent prospective examinations to construct their Fried's frailty phenotype. Childhood conditions in England and Europe included number of books, number of rooms, number of people, presence of running hot or cold water, fixed bath, indoor lavatory and central heating (English Longitudinal Study of Ageing; Survey of Health, Ageing and Retirement in Europe). In the U.S., these were mostly replaced with financial hardship indicators including having to move because of family debt (Health and Retirement Study). Childhood poverty is a latent construct of error-laced recollection and its distal association with frailty phenotype was estimated with a fixed effects probit model. Sensitivity analyses were conducted using a random effects model and stratifying on sex. Childhood poverty associates with higher probabilities of being frail (0.1097 ± 0.0169, p < 0.001) in 29 countries including U.S., England and Europe. Furthermore, women have higher probabilities of being frail (0.3051 ± 0.0152, p < 0.001). Age, education, wealth, marital status and youth illness exert influences on the probabilities of being frail. Evidence is mounting that childhood can last a life time, affecting cognitive muscle and mental functions, and now frailty. This evidence calls for urgent actions to eliminate child poverty on account of its lifelong rewards.

Indexed as

Frail ElderlyFrailtyPovertyAgedAged, 80 and overEnglandEuropeFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesRetrospective StudiesUnited StatesChildhood povertyEnglandEuropeFixed effectsFrailtyHealthy ageingLife courseRandom effectsU.S.

Identifiers

PMID40319157
PMCPMC12049476

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.