Evidence map›Paper›PMID 40318694›Full record

ArticleJournal of the American Medical Directors Association2025

Multimorbidity, Muscle Strength, and Falls among Older Mexican Americans.

Alondra Uribe, Soham Al Snih

Abstract read
In one paragraph

Article in Journal of the American Medical Directors Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Impact of muscle strength decline and exercise intervention on multimorbidity of chronic diseases in older adults.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alondra UribeJohn Sealy School of Medicine, The University of Texas Medical Branch, Galveston, TX, USA.
Soham Al SnihDepartment of Population Health and Health Disparities/School of Public and Population Health, The University of Texas Medical Branch, Galveston, TX, USA; Division of Geriatrics Medicine/Department of Internal Medicine, The University of Texas Medical Branch, Galveston, TX, USA; Sealy Center on Aging, The University of Texas Medical Branch, Galveston, TX, USA. Electronic address: soalsnih@utmb.edu.

Funding

LONGITUDINAL STUDY OF MEXICAN AMERICAN ELDERLY HEALTHR01AG010939 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI MARKIDES, KYRIAKOS S · 1992 to 2022
$14.6M
The Texas Resource Center on Minority Aging Research (RCMAR)P30AG059301 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kyriakos S Markides, Fernando Riosmena · 2018 to 2026
$5.2M
Long-term Health Outcomes in Mexican American Older AdultsR01MD010355 · NIMHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI AL SNIH, SOHAM · 2016 to 2019
$1.9M
NIA NIH HHS P30 AG059301NIA NIH HHS R01 AG010939NIMHD NIH HHS R01 MD010355
6 · The paper itself

Abstract

objectivesMultimorbidity is linked with an increased risk of falls in older adults. The study objective is to determine the relationship of multimorbidity and muscle strength in falls among older Mexican Americans without a history of falls at baseline.

designLongitudinal study. SETTING AND

participantsThis 12-year prospective cohort study included 899 noninstitutionalized Mexican Americans aged ≥75 years residing in Arizona, California, Colorado, New Mexico, and Texas from the Hispanic Established Population for the Epidemiologic Study of the Elderly (HEPESE).

methodsMeasures include the following: sociodemographics, medical conditions, body mass index, disability, handgrip strength (HGS), depressive symptoms, pain, cognitive function, and multimorbidity (≥2 self-reported medical conditions). Participants at baseline were divided into the following 4 groups: high HGS and multimorbidity (n = 349), low HGS and multimorbidity (n = 263), high HGS and without multimorbidity (n = 181), and low HGS and without multimorbidity (n = 104). Generalized estimating equation models estimated the odds ratio (OR) and 95% CI for falls as a function of multimorbidity and HGS group, controlling for all covariates.

resultsThe mean sample age ± SD was 81.0 ± 4.3 years, and 55.9% were female. The OR for falls was 0.70 (95% CI, 0.52-0.94) for those with multimorbidity and high HGS, 0.50 (95% CI, 0.32-0.80) for those without multimorbidity and high HGS, and 0.46 (95% CI, 0.29-0.74) for those without multimorbidity and low HGS, vs those with multimorbidity and low HGS, after controlling for all covariates. CONCLUSIONS AND IMPLICATIONS: Mexican American older adults with multimorbidity and high HGS had a 30% decreased risk of falls over time. Increasing muscle strength through exercise may help prevent falls among those with multimorbidity.

Indexed as

Accidental FallsMexican AmericansMultimorbidityMuscle StrengthAgedAged, 80 and overFemaleHand StrengthHumansLongitudinal StudiesMaleProspective StudiesUnited StatesAgingcomorbiditiesfallsHispanicphysical function

Identifiers

PMID40318694
PMCPMC12218926

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.