ArticleJournal of veterinary internal medicine
Clinical Features That Increase Suspicion of Brucella canis Infection in Dogs With Discospondylitis: A Multicenter Case-Control Study.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Discospondylitis caused by Brucella canis in a dog imported to Sweden.Acta veterinaria Scandinavica · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBrucella canis is an important cause of discospondylitis in dogs, and brucellosis can be challenging to diagnose. Early recognition could aid in early implementation of precautions to limit zoonotic transmission. HYPOTHESIS/
objectivesTo determine whether specific clinical features exist that differentiate Brucella canis infection from other causes of discospondylitis in dogs. ANIMALS: Fifteen dogs with Brucella canis discospondylitis (cases) and 25 dogs with non-Brucella discospondylitis (controls) evaluated between 2010 and 2021.
methodsMulti-institutional retrospective case-control study. Clinical features in cases were compared to those in temporally matched controls using conditional logistic regression analysis. Neurologic examination findings and radiographic findings were documented by a board-certified neurologist and radiologist who were masked to group identity.
resultsNo case had a history of being bred or kennel housing. Cases were younger (median, 2.6 years) than controls (median, 5.7 years) (95% confidence interval [CI] 0.66-1.00). There were no differences in sex or breed. Compared to controls, cases had a lower odds of neurologic deficits (odds ratio [OR] = 0.03; 95% CI 0.00-0.85), higher odds of C2-C5 involvement (OR = 13.0; 95% CI 1.6-106.7), and higher odds of multiple disc site involvement (OR = 12.0, 95% CI 1.5-95.8). They had a lower odds of neutrophilia (OR = 0.11, 95% CI 0.01-0.92), a higher median hematocrit (50.6% versus 43.7%; OR = 1.49, 95% CI 1.09-2.03), and a higher median lymphocyte count (1.8 × 1000/μL vs. 1.1 × 1000/μL; OR = 2.39, 95% CI 1.05-5.45). There was no difference in the radiographic appearance of lesions between groups. CONCLUSIONS AND CLINICAL IMPORTANCE: Brucella canis infection should still be considered in cases of discospondylitis regardless of neuter status, sex, and breeding history. Clinical features exist that should increase suspicion for brucellosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.