Evidence map›Paper›PMID 40317750›Full record

ArticleThe Laryngoscope2025

Association of Dysphonia in Patients With Dysphagia in the United States: A National Database Study.

Linh He, Robin Zhao, James Curtis, Camonia Graham-Tutt, Anaïs Rameau

Abstract read
In one paragraph

Article in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linh HeDepartment of Otolaryngology-Head & Neck Surgery, Weill Cornell Medical College, Sean Parker Institute for the Voice, New York, New York, USA.ORCID 0000-0003-4304-1278
Robin ZhaoDepartment of Otolaryngology-Head & Neck Surgery, Weill Cornell Medical College, Sean Parker Institute for the Voice, New York, New York, USA.
James CurtisDepartment of Otolaryngology-Head & Neck Surgery, Weill Cornell Medical College, Sean Parker Institute for the Voice, New York, New York, USA.ORCID 0000-0002-5677-6364
Camonia Graham-TuttDepartment of Mathematics, Natural and Health Sciences, University of Hawai'i-West O'ahu, Kapolei, Hawaii, USA.
Anaïs RameauDepartment of Otolaryngology-Head & Neck Surgery, Weill Cornell Medical College, Sean Parker Institute for the Voice, New York, New York, USA.ORCID 0000-0003-1543-2634

Funding

Bridge2AI: Voice as a Biomarker of Health - Building an ethically sourced, bioaccoustic database to understand disease like never beforeOT2OD032720 · OD · UNIVERSITY OF SOUTH FLORIDA · PI BENSOUSSAN, YAEL EMILIE, BÉLISLE-PIPON, JEAN-CHRISTOPHE · 2022 to 2025
$18.0M
Developing an App-Based Voice Clinical Decision Support Tool to Augment the Sensitivity of the Bedside Swallow Evaluation in Older AdultsK76AG079040 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Anais Rameau · 2022 to 2026
$972k
NIA NIH HHS K76 AG079040NIH HHS OT2 OD032720
6 · The paper itself

Abstract

objectiveLimited research exists on the prevalence and comorbidity of dysphagia and dysphonia, though prior studies highlight their co-existence in multiple disease cohorts. This study investigates the prevalence of dysphonia in U.S. adults with dysphagia.

methodsA cross-sectional study was conducted using the NIH's All of Us Research Program controlled tier dataset (version 7). Multivariate logistic regression and marginal effects (ME) examined the association of dysphonia in U.S. adults with dysphagia.

resultsAmong 266,612 adults, 24,198 had dysphagia (median age, 67 years; 63% female), and 242,414 did not (median age, 58 years; 61% female). Dysphonia was significantly more prevalent in patients with dysphagia (14% vs. 1.9%, p < 0.001). Multivariate analysis showed a 6.78-fold increase in odds of dysphonia with dysphagia (95% CI 6.47-7.11; ME 9.82%). Dysphagia was significantly associated with dysphonia in patients with head and neck cancer (aOR 2.93; ME 13.51%), stroke (aOR 3.71; ME 14.56%), neurodegenerative conditions (aOR 4.34; ME 13.16%), COPD (aOR 4.33; ME 13.35%), ACDF (aOR 5.24; ME 18.90%), and vocal fold abnormalities (aOR 1.40; ME 7.71%).

conclusionPatients with dysphagia had a 6.78-fold increase in odds of having a diagnosis of dysphonia. Otolaryngologists and speech-language pathologists should consider dysphonia assessment in their patients presenting with dysphagia. LEVEL OF EVIDENCE: 3:

Indexed as

Deglutition DisordersDysphoniaAdultAgedComorbidityCross-Sectional StudiesDatabases, FactualFemaleHumansMaleMiddle AgedPrevalenceUnited Statesdysphagiadysphonialaryngology

Identifiers

PMID40317750
PMCPMC12353530

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.