Evidence map›Paper›PMID 40317650›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

scCompass: An Integrated Multi-Species scRNA-seq Database for AI-Ready.

Pengfei Wang, Wenhao Liu, Jiajia Wang, Yana Liu, Pengjiang Li, Ping Xu, Wentao Cui, Ran Zhang, Qingqing Long, Zhilong Hu and 20 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. scCompass: An Integrated Multi-Species scRNA-seq Database for AI-Ready.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Pengfei WangComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.ORCID https://orcid.org/0000-0003-1075-0684
Wenhao LiuState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Jiajia WangComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Yana LiuState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Pengjiang LiComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Ping XuComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Wentao CuiComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Ran ZhangComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Qingqing LongComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Zhilong HuComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Chen FangState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Jingxi DongState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Chunyang ZhangComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Yan ChenComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Chengrui WangComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Guole LiuState Key Laboratory of Multimodal Artificial Intelligence Systems, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China.
Hanyu XieComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Yiyang ZhangCEMS, NCMIS, HCMS, MDIS, RCSDS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, 100190, China.
Meng XiaoComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Shubai ChenBeijing Key Laboratory of Mobile Computing and Pervasive Device, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China.
Haiping JiangState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
X‐Compass Consortium
Yiqiang ChenBeijing Key Laboratory of Mobile Computing and Pervasive Device, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, 100190, China.
Ge YangState Key Laboratory of Multimodal Artificial Intelligence Systems, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China.
Shihua ZhangCEMS, NCMIS, HCMS, MDIS, RCSDS, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, 100190, China.
Zhen MengComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Xuezhi WangComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.
Guihai FengState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Xin LiState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Yuanchun ZhouComputer Network Information Center, Chinese Academy of Sciences, Beijing, 100083, China.

Funding

CAS Project for Young Scientists in Basic Research YSBR-076Initiative Scientific Research Program, Institute of Zoology, Chinese Academy of Sciences 2023IOZ0102,2024IOZ0101National Key Research and Development Program of China 2024YFF0729200National Key Research and Development Program of China 2024YFF0729201National Natural Science Foundation of China 92470204Pilot Project for Enhancing Original Innovation Capability of the Chinese Academy of Sciences E129L111Strategic Priority Research Program of the Chinese Academy of Sciences XDA0460305toG.F.
6 · The paper itself

Abstract

Emerging single-cell sequencing technology has generated large amounts of data, allowing analysis of cellular dynamics and gene regulation at the single-cell resolution. Advances in artificial intelligence enhance life sciences research by delivering critical insights and optimizing data analysis processes. However, inconsistent data processing quality and standards remain to be a major challenge. Here scCompass is proposed, which provides a comprehensive resource designed to build large-scale, multi-species, and model-friendly single-cell data collection. By applying standardized data pre-processing, scCompass integrates and curates transcriptomic data from nearly 105 million single cells across 13 species. Using this extensive dataset, it is able to identify stable expression genes (SEGs) and organ-specific expression genes (OSGs) in humans and mice. Different scalable datasets are provided that can be easily adapted for AI model training and the pretrained checkpoints with state-of-the-art single-cell foundation models. In summary, scCompass is highly efficient and scalable database for AI-ready, which combined with user-friendly data sharing, visualization, and online analysis, greatly simplifies data access and exploitation for researchers in single-cell biology (http://www.bdbe.cn/kun).

Indexed as

Artificial IntelligenceDatabases, GeneticRNA-SeqSingle-Cell AnalysisAnimalsHumansMiceSingle-Cell Gene Expression AnalysisTranscriptomeAI‐readymulti‐speciesscRNA‐seq databasesingle‐cell

Identifiers

PMID40317650
PMCPMC12224968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.