Evidence map›Paper›PMID 40317314›Full record

ArticleSurgery today2025

Impact of an improvement in the early left ventricular ejection fraction on the 1-year clinical outcomes and its predictors after transcatheter aortic valve replacement.

Ikuko Shibasaki, Yusuke Takei, Suguru Hirose, Michiaki Tokura, Masahiro Tezuka, Shohei Yokoyama, Ryujiro Suzuki, Riichi Nishikawa, Shu Inami, Yasuo Haruyama and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ikuko ShibasakiDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsugagun, Tochigi, 321-0293, Japan. sibasaki@dokkyomed.ac.jp.ORCID http://orcid.org/0000-0002-4017-8503
Yusuke TakeiDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsugagun, Tochigi, 321-0293, Japan.
Suguru HiroseDepartment of Cardiovascular Medicine, Dokkyo Medical University School of Medicine, Tochigi, Japan.
Michiaki TokuraDepartment of Cardiovascular Medicine, Dokkyo Medical University School of Medicine, Tochigi, Japan.
Masahiro TezukaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsugagun, Tochigi, 321-0293, Japan.
Shohei YokoyamaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsugagun, Tochigi, 321-0293, Japan.
Ryujiro SuzukiDepartment of Cardiovascular Medicine, Dokkyo Medical University School of Medicine, Tochigi, Japan.
Riichi NishikawaDepartment of Cardiovascular Medicine, Dokkyo Medical University School of Medicine, Tochigi, Japan.
Shu InamiDepartment of Cardiovascular Medicine, Dokkyo Medical University School of Medicine, Tochigi, Japan.
Yasuo HaruyamaCenter for Research Collaboration and Support, Dokkyo Medical University School of Medicine, Tochigi, Japan.
Shigeru ToyodaDepartment of Cardiovascular Medicine, Dokkyo Medical University School of Medicine, Tochigi, Japan.
Hirotsugu FukudaDepartment of Cardiac and Vascular Surgery, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsugagun, Tochigi, 321-0293, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe evaluated the 1-year clinical outcomes (all-cause mortality, heart failure rehospitalization, and their composite) in patients with severe aortic stenosis (AS) and a preoperative left ventricular ejection fraction (LVEF) < 50% who underwent transcatheter aortic valve replacement (TAVR), and examined the baseline factors predicting ≥ 10% early LVEF improvement.

methodsWe retrospectively analyzed 44 patients who underwent TAVR and divided them into Group R (≥ 10% LVEF improvement, n = 25) or Group N (< 10% improvement, n = 19). A Kaplan-Meier analysis was used to assess the survival rates, and multivariable logistic regression was applied to identify the predictors of LVEF improvement.

resultsThe mean patient age was 84.8 ± 4.8 years, and 40.9% were male. Post-TAVR, 56.8% of patients showed ≥ 10% LVEF improvement (mean increase: 16.7 ± 6.1%). The one-year mortality was similar between the groups (p = 0.383), whereas the composite endpoint tended to be higher in Group N (0.4% vs. 21.1%, p = 0.072). The peak aortic valve velocity was the only significant predictor (OR = 0.255, p = 0.048; cutoff: 4.45 m/s, sensitivity, 0.840; specificity, 0.684).

conclusionIn patients with severe AS and a preoperative LVEF of < 50%, 56.8% demonstrated a significant early LVEF improvement post-TAVR. Patients with a ≥ 10% improvement had a significantly lower 1-year mortality rate.

Indexed as

Aortic Valve StenosisStroke VolumeTranscatheter Aortic Valve ReplacementVentricular Function, LeftAgedAged, 80 and overAortic ValveFemaleHeart FailureHumansMalePatient ReadmissionRetrospective StudiesSeverity of Illness IndexSurvival RateTime FactorsLeft ventricular ejection fractionSevere aortic stenosisTranscatheter aortic valve replacement

Identifiers

PMID40317314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.