Evidence map›Paper›PMID 40316960›Full record

SynthesisBMC public health2025

Association between ambient air pollution exposure and pregnancy outcomes in women treated with assisted reproductive technology: an updated systematic review and meta-analysis.

Jian-Chao Qiao, Liang-Jie Sun, Pin-Peng Xie, Zhuo-Yan Li, Meng-Yue Zhang, Si-Yu Gui, Xin-Chen Wang, Jian-Kang Yang, Cheng-Yang Hu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jian-Chao Qiao *Department of Clinical Medicine, The Second School of Clinical Medicine, Anhui Medical University, 81 Meishan Road, Hefei, 230032, China.
Liang-Jie Sun *Department of Clinical Medicine, The Second School of Clinical Medicine, Anhui Medical University, 81 Meishan Road, Hefei, 230032, China.
Pin-Peng XieDepartment of Clinical Medicine, The Second School of Clinical Medicine, Anhui Medical University, 81 Meishan Road, Hefei, 230032, China.
Zhuo-Yan LiDepartment of Clinical Medicine, The Second School of Clinical Medicine, Anhui Medical University, 81 Meishan Road, Hefei, 230032, China.
Meng-Yue ZhangDepartment of Clinical Medicine, The Second School of Clinical Medicine, Anhui Medical University, 81 Meishan Road, Hefei, 230032, China.
Si-Yu GuiDepartment of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, China.
Xin-Chen WangDepartment of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, 230601, China.
Jian-Kang YangDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, China.
Cheng-Yang HuDepartment of Humanistic Medicine, School of Humanistic Medicine, Anhui Medical University, 81 Meishan Road, Hefei, 230032, China. cy.hu@ahmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmbient air pollution has been recognized as a potential threat to reproductive system function. However, studies investigating the relationship between air pollutants and pregnancy outcomes, particularly in the context of assisted reproductive technology (ART), has yielded inconsistent findings.

methodsThis study conducted an updated comprehensive search to identify observational studies published before October 14, 2023, that examined the associations between air pollution exposure and pregnancy outcomes among women undergoing ART. Meta-analysis using random effects models were employed to calculate pooled risk estimates of clinical pregnancy, biochemical pregnancy, and live birth.

resultsA total of 20 studies were included in the systematic review and meta-analysis, with 12 studies included in the quantitative synthesis. The results revealed that exposure to carbon monoxide (CO) (RR = 0.949, 95% CI: 0.900, 0.999; I

conclusionsOur study highlights the potential association between air quality and ART outcomes, underscoring the need for improvements in air quality to enhance reproductive success.

Indexed as

Air PollutantsAir PollutionEnvironmental ExposurePregnancy OutcomeReproductive Techniques, AssistedFemaleHumansPregnancyAir PollutantsAmbient air pollutionARTAssisted reproductive technologyBiochemical pregnancyClinical pregnancyLive birth

Identifiers

PMID40316960
PMCPMC12046897

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.