Evidence map›Paper›PMID 40316946›Full record

ArticleBMC plant biology2025

Genome-wide characterization and expression profiling of FIMBRIN gene family members in response to abiotic stress in Medicago sativa.

Juan Wang, Xinru Su, Zhicheng Jia, Wenxin Peng, Liru Dou, Peisheng Mao

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Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Juan WangCollege of Grassland Science and Technology, China Agricultural University, Beijing, 100193, China.
Xinru SuCollege of Grassland Science and Technology, China Agricultural University, Beijing, 100193, China.
Zhicheng JiaCollege of Grassland Science and Technology, China Agricultural University, Beijing, 100193, China.
Wenxin PengCollege of Grassland Science and Technology, China Agricultural University, Beijing, 100193, China.
Liru DouCollege of Grassland Science and Technology, China Agricultural University, Beijing, 100193, China. douliru@cau.edu.cn.
Peisheng MaoCollege of Grassland Science and Technology, China Agricultural University, Beijing, 100193, China. maops@cau.edu.cn.

Funding

CARS (CARS-34) CARS-34
6 · The paper itself

Abstract

backgroundAlfalfa is widely regarded as one of the most important forage crops globally. However, its growth and development are primarily constrained by various abiotic stresses. FIMBRINs are crucial actin-binding proteins involved in regulating cellular dynamics in plants under various stress conditions and during developmental processes. The Fimbrin (FIM) gene family has been reported only in Arabidopsis, while a comprehensive identification of the FIM gene family in alfalfa and the responses of its members to abiotic stresses remain unclear.

resultsIn this study, six MsFIM genes were identified in the alfalfa genome, distributed across three chromosomes. Phylogenetic analysis grouped these genes into four clades, all containing the conserved CH domain. Gene duplication events suggested that large fragment duplications contribute to gene amplification. Furthermore, cis-regulatory element analysis highlighted their pivotal roles in plant development and response to external abiotic stresses. RT-qPCR analyses revealed that the MsFIM genes exhibited differential expression across various tissues, with predominant expression in flowers, stems, and leaves. The MsFIM genes showed elevated expression under abiotic stresses (drought, cold, and salt) as well as hormone treatment (abscisic acid, ABA), suggesting that they served as positive regulators in alfalfa's resistance to abiotic stresses and its growth and development.

conclusionsThis study investigates the MsFIM genes in alfalfa, further analyzing their potential roles in plant development and response to abiotic stresses. These findings will provide novel insights into the molecular mechanisms of alfalfa's stress response.

Indexed as

Medicago sativaPlant ProteinsStress, PhysiologicalGene Expression ProfilingGene Expression Regulation, PlantGenes, PlantGenome, PlantMultigene FamilyPhylogenyPlant ProteinsAbiotic stressExpression patternsFimbrin gene familyGenome-wide analysisMedicago sativa

Identifiers

PMID40316946
PMCPMC12049050

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