Evidence map›Paper›PMID 40316924›Full record

ArticleBMC genomics2025

Exploring Y-chromosomal STRs and SNPs for forensic and genetic insights in the Jiangsu Han population.

Min Li, Han Zhang, Ruiyang Tao, Anqi Chen, Peng Zhou, Chunjiang Yu, Yingnan Bian, Suhua Zhang, Chen Fang, Chengtao Li

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Min Li *Department of Forensic Medicine, School of Clinical and Basic Medical Sciences, Shandong First Medical University& Shandong Academy of Medical Sciences, Jinan, 250117, China.
Han Zhang *Institute of Forensic Science, Fudan University, Shanghai, 200032, China.
Ruiyang TaoShanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Key Laboratory of Forensic Science, Academy of Forensic Sciences, Ministry of Justice, Shanghai, 200063, China.
Anqi ChenInstitute of Forensic Science, Fudan University, Shanghai, 200032, China.
Peng ZhouDepartment of Forensic Medicine, School of Clinical and Basic Medical Sciences, Shandong First Medical University& Shandong Academy of Medical Sciences, Jinan, 250117, China.
Chunjiang YuDepartment of Forensic Medicine, School of Clinical and Basic Medical Sciences, Shandong First Medical University& Shandong Academy of Medical Sciences, Jinan, 250117, China.
Yingnan BianShanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Key Laboratory of Forensic Science, Academy of Forensic Sciences, Ministry of Justice, Shanghai, 200063, China.
Suhua ZhangInstitute of Forensic Science, Fudan University, Shanghai, 200032, China.
Chen FangDepartment of Forensic Medicine, School of Clinical and Basic Medical Sciences, Shandong First Medical University& Shandong Academy of Medical Sciences, Jinan, 250117, China. chenfangyulix@126.com.
Chengtao LiInstitute of Forensic Science, Fudan University, Shanghai, 200032, China. lichengtao@fudan.edu.cn.

Funding

National Natural Science Foundation of China 82002006Natural Science Foundation of Shandong Province ZR2022QH337Qingchuang Talents Induction Program of Shandong Higher Education Institution 2022 Forensic medicine innovation team
6 · The paper itself

Abstract

Y-chromosome short tandem repeats (Y-STRs) and single nucleotide polymorphisms (Y-SNPs) are valuable genetic markers used for individual identification, forensic applications, and the study of paternal lineage history. This study analyzed the genetic polymorphism and paternal genetic structure of the Han population in Jiangsu Province by examining 374 unrelated male individuals using 29 Y-STRs and 183 Y-SNPs. Forensic parameters were calculated, and the discriminatory power of five Y-STR systems (MHT, EXT, PPY12, Yfiler, and Y29) was compared. Genetic structure was assessed in the context of the Jiangsu Han and other Chinese populations. Results showed that the Y29 system had the highest discriminatory capacity, identifying 374 unique haplotypes with HD and DC values of 1. Seven major haplogroups (C, D, J, K, O, Q, R) and 83 terminal haplogroups were identified, with haplogroup O being the most predominant (approximately 85%). Subdivision of haplogroup O revealed that the Jiangsu Han population exhibits genetic characteristics of both Southern and Northern Han groups. Population genetic analyses further confirmed that the Jiangsu Han clustered closely with Southern Han populations. Genetic admixture results revealed that the Jiangsu Han population derives 89% of their ancestry from Southern Han populations, while retaining 11% Northern Han contributions. The study provides valuable insights into the genetic structure of the Jiangsu Han population, with significant implications for forensic genetics, anthropological research, and broader population genetics studies.

Indexed as

Asian PeopleChromosomes, Human, YEthnicityForensic GeneticsGenetics, PopulationMicrosatellite RepeatsPolymorphism, Single NucleotideChinaHaplotypesHumansMalePhylogenyForensic characteristicsGenetic substructureHan populationsY-SNPsY-STRs

Identifiers

PMID40316924
PMCPMC12048932

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