Evidence map›Paper›PMID 40316892›Full record

ArticleBMC plant biology2025

Withania coagulans-mediated green synthesis of silver nanoparticles: characterization and assessment of their phytochemical, antioxidant, toxicity, and antimicrobial activities.

Amjid Khan, Tahira Younis, Muhammad Anas, Muhammad Ali, Zabta Khan Shinwari, Ali Talha Khalil, Khurram Shahzad Munawar, Hamza Elsayed Ahmed Mohamed, Khaoula Hkiri, Malik Maaza and 2 more

Abstract read
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amjid KhanDepartment of Plant Sciences, Faculty of Biological Sciences, Quaid -i- Azam University, Islamabad, 45320, Pakistan.
Tahira YounisDepartment of Plant Sciences, Faculty of Biological Sciences, Quaid -i- Azam University, Islamabad, 45320, Pakistan.
Muhammad AnasDepartment of Plant Sciences, Faculty of Biological Sciences, Quaid -i- Azam University, Islamabad, 45320, Pakistan.
Muhammad AliDepartment of Biotechnology, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Zabta Khan ShinwariDepartment of Plant Sciences, Faculty of Biological Sciences, Quaid -i- Azam University, Islamabad, 45320, Pakistan. shinwari2008@gmail.com.
Ali Talha KhalilDepartment of Pathology, Lady Reading Hosipital Medical Teaching Institution, Peshawar, KP, 25000, Pakistan.
Khurram Shahzad MunawarDepartment of Chemistry, University of Mianwali, Mianwali, Punjab, 42200, Pakistan.
Hamza Elsayed Ahmed MohamedUNESCO UNISA Africa Chair in Nanoscience and Nanotechnology, College of Graduate Studies, University of South Africa, Pretoria, South Africa.
Khaoula HkiriUNESCO UNISA Africa Chair in Nanoscience and Nanotechnology, College of Graduate Studies, University of South Africa, Pretoria, South Africa.
Malik MaazaUNESCO UNISA Africa Chair in Nanoscience and Nanotechnology, College of Graduate Studies, University of South Africa, Pretoria, South Africa.
Mahmoud F SeleimanDepartment of Plant Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Naeem KhanAgronomy Department, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, 32611, USA. naeemkhan@ufl.edu.

Funding

King Saud University PSPD2025R751
6 · The paper itself

Abstract

backgroundIn this study, we report the biofabrication of silver nanoparticles (Ag-NPs) using aqueous leaf extracts of Withania coagulans, which act as both reducing and capping agents. The goal was to synthesize and characterize the silver nanoparticles and evaluate their biological properties.

resultsThe silver nanoparticles were characterized by multiple techniques including UV-visible spectroscopy, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Raman spectroscopy, scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), high-resolution transmission electron microscopy (HRTEM), zeta potential, dynamic light scattering (DLS), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). A surface plasmon resonance peak was observed at 420 nm, and the XRD pattern indicated highly crystalline Ag-NPs with a crystallite size of 39.76 nm. SEM and HRTEM revealed irregular morphology with an average particle diameter of 26.63 nm. Zeta potential of -21.4 mV indicated relatively stable nanoparticles. FTIR spectra displayed significant peaks at 3269, 2921, 1628, 1513, and 1385 cm⁻

conclusionsThe Withania coagulans leaf-extract-mediated silver nanoparticles exhibit remarkable antioxidant, phytochemical, and antimicrobial properties, suggesting potential for commercial applications in various biomedical and agricultural fields.

Indexed as

Anti-Infective AgentsAntioxidantsMetal NanoparticlesSilverWithaniaAnimalsArtemiaGreen Chemistry TechnologyPhytochemicalsPlant ExtractsPlant LeavesSpectroscopy, Fourier Transform InfraredAnti-Infective AgentsAntioxidantsPhytochemicalsPlant ExtractsSilverAntimicrobial activityAntioxidantGreen synthesisNanotechnologySilver nanoparticles

Identifiers

PMID40316892
PMCPMC12048944

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.