Evidence map›Paper›PMID 40316863›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025

The impact of the patient's plasma volume on the amount of fresh frozen plasma needed to normalize the thromboelastographic reaction time.

Mordechai Caplan, Natalia Torres-Acevedo, Patrizio Petrone, Lindsay Beach, Reddy H Srinivas, Anna Liveris, Corrado P Marini, John McNelis

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Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mordechai CaplanDepartment of Surgery, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Natalia Torres-AcevedoDepartment of Surgery, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Patrizio PetroneNYU Grossman Long Island School of Medicine, Mineola, NY, USA. patrizio.petrone@gmail.com.
Lindsay BeachDepartment of Surgery, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Reddy H SrinivasDepartment of Surgery, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Anna LiverisDepartment of Surgery, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Corrado P MariniDepartment of Surgery, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
John McNelisDepartment of Surgery, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCorrection of a prolonged CK-TEG R-time requires the administration of fresh frozen plasma (FFP). However, the relationship between the volume required to normalize the R-time and the patient's plasma volume (PV

methods30 patients receiving FFP to normalize their R-times were analyzed from the standpoint of sex distribution and R-time response to the administration of FFP. PV

resultsFemales had a smaller PV

conclusionsWe conclude that: 1) The amount of FFP required to normalize the R-time is lower than the recommended dose of 10-20 ml/kg: 2) 6.8 ml/kg of FFP, corresponding to an initial administration of two units of FFP (~ 500 ml) will provide an increase of 15.6% in the concentration of coagulation factors sufficient to normalize the R-time: 3) The assessment of PV

Indexed as

Blood Component TransfusionPlasmaPlasma VolumeThrombelastographyAdultAgedFemaleHematocritHumansMaleMiddle AgedSex FactorsConventional coagulation testsFresh frozen plasmaPlasma volumeReaction timeTEG

Identifiers

PMID40316863

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.