Evidence map›Paper›PMID 40316859›Full record

SynthesisNeurosurgical review2025

Retreatment rate and strategies for recurrent and residual aneurysms after Woven EndoBridge (WEB) treatment: a comprehensive systematic review and meta-analysis.

Ali Mortezaei, Forough Yazdanian, Mohammad Mirahmadi Eraghi, Farid Qoorchi Moheb Seraj, Romulo Augusto Andrade de Almeida, Parsa Saberian, Mohammad Amin Habibi, Justin H Granstein, Humain Baharvahdat, Redi Rahmani and 1 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ali MortezaeiGonabad University of Medical Sciences, Gonabad, Iran.
Forough Yazdanian *Neurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Mohammad Mirahmadi Eraghi *School of Medicine, Islamic Azad University, Qeshm International Branch, Qeshm, Iran.
Farid Qoorchi Moheb SerajNeurosurgical Department, Neurovascular Section, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Romulo Augusto Andrade de AlmeidaDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Parsa SaberianFaculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Mohammad Amin HabibiDepartment of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Justin H GransteinNeurosurgical Service, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Humain BaharvahdatDepartment of Interventional Neuroradiology, Rothschild Foundation Hospital, Paris, France.
Redi RahmaniDepartment of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Robert M StarkeDepartment of Neurological Surgery, Radiology, Neurosciences, Pharmacology, University of Miami School of Medicine, Miami, FL, USA. rstarke@med.miami.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Woven Endo Bridge (WEB) is a flow diverter device used to treat wide-necked intracranial aneurysms. We conducted a systematic review and meta-analysis to determine the retreatment rate and strategies following aneurysmal recurrence after WEB treatment. A systematic literature search was conducted through four electronic databases. The Cochrane risk of bias tool for non-randomized trials (ROBINS-I) was used for risk of bias assessment. A meta-analysis and meta-regression were performed on relevant variables. A total of 29 studies with 2067 patients were included. Initially treated aneurysms had an adequate occlusion rate of 84.7% (20 studies, 980/1156, 95%CI: 79%-89%) at the last follow-up. The overall retreatment rate was 8.6% (24 studies, 251/2893, 95%CI: 6.5%-10.9%). Following retreatment, the immediate complete occlusion rate post retreatment and complete occlusion rate at last follow-up were 52% (six studies, 95%CI, 11%-91%) and 65% (six studies, 77/120, 95%CI: 56%-73%) respectively. Stent-assisted coiling achieved a 100% (95%CI: 57%-100%, P-value < 0.01) immediate adequate occlusion rate and 74% complete occlusion rate (95%CI: 16%-100%, P-value = 0.63) at last follow-up, which was higher than clipping, coiling, and flow diversion. On meta-regression, aneurysm height and neck width significantly associated with higher retreatment rate. The current meta-analysis showed a 9% retreatment rate after initial aneurysms treatment with WEB and overall adequate retreatment occlusion was high. Although stent-assisted coiling showed a higher adequate occlusion rate post-operatively, there was no significant difference between retreatment strategies in long-term radiological outcomes.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmHumansRecurrenceRetreatmentStentsTreatment OutcomeAneurysmIntrasaccular Flow DiverterRetreatmentWoven EndoBridge

Identifiers

PMID40316859
PMCPMC12048415

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.