Evidence map›Paper›PMID 40316791›Full record

ReviewAesthetic plastic surgery2025

The Clinical Impact of Different Cryolipolysis Protocols: An Integrative Review.

Patricia Brassolatti, Ana Laura Martins de Andrade, Michele Akemi Nishioka, Fabiele Chieregato, Giovanna Pontes Vidal, Kacie Letícia Ribas Machado Lemes, Franciele Souza Doneda, José Ricardo de Souza, Elizabete Loro de Oliveira Gonçalves, Laura Ferreira de Rezende

Abstract readReviewComparative Study
PubMed Publisher
In one paragraph

Review in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Patricia BrassolattiDepartment of Research, Development, and Innovation at Brazilian Medical Equipment Industry - Ibramed, Amparo/SP, Brazil.
Ana Laura Martins de AndradePostgraduate Program in Biomedical Engineering, Universidade Brasil, São Paulo - SP, Brazil. anandrade90@yahoo.com.br.ORCID 0000-0003-1137-7180
Michele Akemi NishiokaDepartment of Research, Development, and Innovation at Brazilian Medical Equipment Industry - Ibramed, Amparo/SP, Brazil.
Fabiele ChieregatoDepartment of Research, Development, and Innovation at Brazilian Medical Equipment Industry - Ibramed, Amparo/SP, Brazil.
Giovanna Pontes VidalPostgraduate Program in Biomedical Engineering, Universidade Brasil, São Paulo - SP, Brazil.
Kacie Letícia Ribas Machado LemesDepartment of Research, Development, and Innovation at Brazilian Medical Equipment Industry - Ibramed, Amparo/SP, Brazil.
Franciele Souza DonedaDepartment of Research, Development, and Innovation at Brazilian Medical Equipment Industry - Ibramed, Amparo/SP, Brazil.
José Ricardo de SouzaIbramed Company - Brazilian Medical Equipment Industry, Amparo/SP, Brazil.
Elizabete Loro de Oliveira GonçalvesDepartment of Physiotherapy, Centro Universitário das Faculdades Associadas de Ensino - UNIFAE, São João da Boa Vista - SP, Brazil.
Laura Ferreira de RezendeDepartment of Physiotherapy, Centro Universitário das Faculdades Associadas de Ensino - UNIFAE, São João da Boa Vista - SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCryolipolysis is one of the main technologies used as a non-invasive treatment for reducing fat located in different body regions. The literature demonstrates significant effects in reducing fat content and indicates the safety of the technique, since the risks are low and can be avoided by taking a good initial history. The main results indicate approximately 20% reduction after treatments; however, the clinical protocols studied present significant differences related to the temperature used and the treatment time in addition to the difference between the number of exposures and the number of areas possible to be treated in the same session.

objectiveTherefore, this review aimed to identify the treatment protocols presented by the authors and compare the results obtained, to clarify which protocols presented significant results to be considered in clinical use, in addition to assisting in the construction of new protocols for future applications.

methodsIn the search carried out on PubMed, Lilacs and Embase, 32 articles were selected, all of which were considered for this review.

resultsThe results obtained by evaluating the studies demonstrated differences mainly in the regions of application, application time, with the most used temperature being close to - 10 °C.

conclusionThe results found related to the technique had positive effects on all protocols, which makes it difficult to discuss the main findings and choose and/or highlight the most promising protocol. NO LEVEL ASSIGNED: This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

CryosurgeryCryotherapyLipectomyFemaleHumansMaleRisk AssessmentTreatment OutcomeCryolipolysisFatProtocols

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.