ArticleScientific reports2025
Carbon monoxide and nitric oxide diffusion capacity of formerly exposed asbestos workers with high-resolution computed tomography in a cross-sectional study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Pulmonary diffusing capacity for nitric oxide in disease: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2026Article
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8 authors.
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Abstract
Asbestos exposure can induce pulmonary fibrosis known as asbestosis, and pleural thickening, as well as various cancers. Although lung diffusion capacity (DL) including nitric oxide (NO) is assumed to be more sensitive than carbon monoxide (CO), its added value in assessment of pneumoconiosis has not been investigated yet. 371 formerly exposed workers visiting the outpatient clinic for assessment including pulmonary function testing with DL and low-dose high resolution computed tomography between 2018 and 2021 were included. Subgroups were formed depending on findings in low-dose high resolution computed tomography classified according to ICOERD. Receiver operating characteristic curve (ROC) analysis revealed some diagnostic accuracy for DLNO (AUC = 0.73; 95% confidence interval 0.64-0.82) and DLCO (AUC = 0.70; 95% confidence interval 0.60-0.79) regarding asbestosis, but not per unit alveolar volume. DLCO and DLNO correlated strongly with a decreasing score of irregular opacities according to ICOERD (ρ
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