Evidence map›Paper›PMID 40316467›Full record

ArticleTrends in cancer2025

Inciting commensal human papillomavirus immunity to combat cancer.

Natalie E Fulton, Thomas D Horn, Shadmehr Demehri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Natalie E FultonCenter for Cancer Immunology, Krantz Family Center for Cancer Research, Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Thomas D HornDepartment of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: thorn@mgh.harvard.edu.
Shadmehr DemehriCenter for Cancer Immunology, Krantz Family Center for Cancer Research, Cutaneous Biology Research Center, Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: sdemehri1@mgh.harvard.edu.

Funding

Immunity to commensal papillomaviruses for cancer therapyR01CA251755 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DEMEHRI, SHADMEHR, JOH, JOONGHO JOHN · 2021 to 2025
$2.6M
NCI NIH HHS R01 CA251755
6 · The paper itself

Abstract

The incidence of squamous cell carcinoma (SCC) is rising, especially in immunosuppressed individuals, highlighting the need for new prevention strategies. Commensal human papillomaviruses (cHPVs) are associated with cutaneous SCC (cSCC) in immunosuppressed patients. Because of the intricate interactions between T cell immunity and cHPVs in virus-colonized tissues, we propose that enhancing T cell immunity against cHPVs through vaccination could suppress SCC.

Indexed as

Carcinoma, Squamous CellPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesSkin NeoplasmsHuman Papillomavirus VirusesHumansImmunocompromised HostT-LymphocytesPapillomavirus Vaccines

Identifiers

PMID40316467
PMCPMC12240701

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.