Evidence map›Paper›PMID 40316140›Full record

ArticleEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists2025

Use of Neck Ultrasound as Surveillance in Older Adults With Thyroid Cancer.

Nina Francis-Levin, Edward Shao, Jacob Ortlieb, Brittany Gay, Mousumi Banerjee, Maria Papaleontiou, Megan R Haymart

Abstract read
In one paragraph

Article in Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Nina Francis-LevinDivision of Metabolism, Endocrinology & Diabetes, University of Michigan, Ann Arbor, Michigan.
Edward ShaoDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan.
Jacob OrtliebAI & Digital Health Innovation, University of Michigan, Ann Arbor, Michigan.
Brittany GayDivision of Metabolism, Endocrinology & Diabetes, University of Michigan, Ann Arbor, Michigan.
Mousumi BanerjeeDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan.
Maria PapaleontiouDivision of Metabolism, Endocrinology & Diabetes, University of Michigan, Ann Arbor, Michigan; Institute of Gerontology, University of Michigan, Ann Arbor, Michigan.
Megan R HaymartDivision of Metabolism, Endocrinology & Diabetes, University of Michigan, Ann Arbor, Michigan. Electronic address: meganhay@med.umich.edu.

Funding

TRAINING PROGRAM IN ENDOCRINOLOGY AND METABOLISM.T32DK007245 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RICHARD J. AUCHUS · 1986 to 2026
$7.2M
Risk-stratified care for thyroid cancer survivorsR01CA281976 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Megan Rist Haymart · 2024 to 2026
$2.0M
Optimizing Care for Older Adults through Thyroid Hormone DeprescribingR01AG079833 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PAPALEONTIOU, MARIA · 2023 to 2024
$1.6M
NCI NIH HHS R01 CA281976NIA NIH HHS R01 AG079833NIDDK NIH HHS T32 DK007245
6 · The paper itself

Abstract

objectiveClose to one-quarter of thyroid cancers occur in older adults (ie, aged ≥ 65). This group also has other comorbidities and higher risk of death from other causes. Data on optimal neck ultrasound use for thyroid cancer surveillance in older adults are limited.

methodsWe identified patients aged ≥ 65 years diagnosed with thyroid cancer using data from the Centers for Medicare & Medicaid Services linked to health data from University of Michigan between 2016-2021 (median follow-up 3 years, range 0-6 years). We assessed demographic characteristics, comorbidities, frequency of neck ultrasound, and cause of death.

resultsOf the 2007 patients diagnosed with thyroid cancer, median age was 74 years (range 65-100) and 65.1% were female. Overall, 76 (3.8%) died of thyroid cancer, and 259 (12.9%) died of other causes. There were more comorbidities in the cohort who died of other causes during the study period, eg, 179 (69.1%) in the cohort who died of other causes had heart disease compared with 868 (43.3%) of those in the entire cohort. Patients who died of other causes received a mean of 1.36 neck ultrasounds (range 0-12) and the remainder of the cohort received a mean of 2.38 neck ultrasounds (range 0-26) during the study period, P < .001.

conclusionsOlder adults with thyroid cancer are more likely to die of causes other than thyroid cancer. To improve high-value care in older adults with thyroid cancer and high-risk of death from other causes, there is need for individualized plans for neck ultrasound use.

Indexed as

NeckThyroid NeoplasmsAgedAged, 80 and overComorbidityFemaleHumansMaleUltrasonographyUnited StatescomorbiditiesMedicare dataneck ultrasoundolder adultsthyroid cancer

Identifiers

PMID40316140
PMCPMC12303757

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.