Evidence map›Paper›PMID 40315740›Full record

ArticleDrug and alcohol dependence2025

Characteristics associated with forced treatment discontinuation among people who use drugs in Rhode Island.

Evelyn Lai, Katie B Biello, Jane A Buxton, Brandon D L Marshall, Alexandria Macmadu

Abstract read
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In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Evelyn LaiDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA. Electronic address: evelyn_lai@brown.edu.
Katie B BielloDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA; Department of Behavioral and Social Sciences, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA; Center for Health Promotion and Health Equity, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA; The Fenway Institute, Fenway Health. Electronic address: katie_biello@brown.edu.
Jane A BuxtonSchool of Population and Public Health, The University of British Columbia, Vancouver, British Columbia, Canada; BC Centre for Disease Control, Vancouver, British Columbia, Canada. Electronic address: jane.buxton@ubc.ca.
Brandon D L MarshallDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA. Electronic address: brandon_marshall@brown.edu.
Alexandria MacmaduDepartment of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI, USA. Electronic address: alexandria_macmadu@brown.edu.

Funding

The Rhode Island Young Adult Prescription and Illicit Drug Study (RAPIDS): Responding to Fentanyl and Associated HarmsR01DA047975 · NIDA · BROWN UNIVERSITY · PI MARSHALL, BRANDON DAVID LEWIS · 2019 to 2023
$3.8M
NIDA NIH HHS R01 DA047975
6 · The paper itself

Abstract

backgroundA barrier to remaining in substance use treatment in the U.S. is abstinence-based policies, which can lead to premature treatment termination. In this study, we examine factors associated with forced treatment discontinuation due to substance use among participants in the Rhode Island Prescription and Illicit Drug Study (RAPIDS).

methodsWe examined baseline data from RAPIDS participants (who enrolled between August 2020 and February 2023) and who reported any history of enrollment in substance use treatment programs. Modified Poisson regression was used to assess sociodemographic, drug use behavior, and clinical characteristics associated with forced treatment discontinuation due to substance use. The type of treatment from which participants were removed and the drug(s) that were implicated in the removal were also summarized.

resultsAmong 406 eligible participants, 96 (24 %) experienced forced treatment discontinuation due to drug or alcohol use. The most frequently reported program from which participants were removed was residential treatment (75 %). The most frequently reported drug that was implicated in the removal was crack cocaine (33 %). In the modified Poisson analysis, regular use of powder cocaine was associated with experiencing forced treatment discontinuation (adjusted prevalence ratio = 1.50; 95 % confidence interval: 1.05, 2.15).

conclusionsForced treatment discontinuation due to substance use is common, particularly in residential drug treatment. Our findings suggest a need for enhanced access to evidence-based treatments for stimulant use disorders. Persisting racial/ethnic disparities in treatment access underscores the need for strategies to ensure racial and ethnic equity in substance use treatment access and retention in care.

Indexed as

Patient ComplianceSubstance-Related DisordersWithholding TreatmentAdultFemaleHumansMaleMiddle AgedRhode IslandYoung AdultAbstinence-based policiesPeople who use drugsStimulant use disorderTreatment discontinuation

Identifiers

PMID40315740
PMCPMC13482760

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.