Evidence map›Paper›PMID 40315205›Full record

ArticlePloS one2025

Menstrual cycle and perceived stress predict performance on the mnemonic similarity task.

Mateja Perović, Michael L Mack

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mateja PerovićDepartment of Psychology, University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0003-3865-8011
Michael L MackDepartment of Psychology, University of Toronto, Toronto, Canada.ORCID https://orcid.org/0000-0001-5155-7413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A growing body of literature demonstrates strong effects of ovarian hormones on the hippocampus and adjacent structures. However, resulting impacts on human cognition remain unclear. Addressing this gap, we examine pattern separation ability, a core hippocampal process, across the menstrual cycle using the mnemonic similarity task as a behavioral index (N = 183). We find a non-linear effect of the menstrual cycle, with pattern separation performance peaking in the high-estradiol, late follicular phase and reaching its lowest point during the mid-luteal phase, which is characterized by moderate estradiol and high progesterone levels. Additionally, we find that perceived stress may facilitate pattern separation performance. These results point to the importance of ovarian hormones for human cognition, reveal novel effects of perceived stress on mnemonic similarity task performance, and provide preliminary evidence of possible effects of menstrual cycle phase on neural pathways involved in pattern separation.

Indexed as

Menstrual CycleStress, PsychologicalAdolescentAdultCognitionEstradiolFemaleHumansProgesteroneTask Performance and AnalysisYoung AdultEstradiolProgesterone

Identifiers

PMID40315205
PMCPMC12047775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.