Evidence map›Paper›PMID 40315203›Full record

ArticlePloS one2025

The experiences of high-risk young adults with type 1 diabetes transitioning to real-time continuous glucose monitoring - A thematic analysis.

Vicky McKechnie, Parizad Avari, Pei Chia Eng, Rebecca Unsworth, Monika Reddy, Stephanie A Amiel, Victoria Salem, Shivani Misra

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vicky McKechnieDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.ORCID 0000-0003-4480-5188
Parizad AvariDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.ORCID 0000-0001-9047-3589
Pei Chia EngDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.ORCID 0000-0002-4172-1344
Rebecca UnsworthDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Monika ReddyDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
Stephanie A AmielDepartment of Diabetes, Faculty of Life Sciences, King's College London, London, United Kingdom.
Victoria SalemDepartment of Bioengineering, Imperial College London, London, United Kingdom.
Shivani MisraDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.ORCID 0000-0003-2886-0726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReal-time continuous glucose monitoring (rtCGM) is now the standard care for people with type 1 diabetes. However, whilst its impact on glycaemic outcomes is well-documented, its psychosocial effects, particularly in young adults experiencing extreme hyperglycaemia, remain poorly understood.

objectivesWe aimed to explore the psychosocial impact of rtCGM on young adults with extreme hyperglycaemia who thus far have not been studied extensively. RESEARCH DESIGN AND

methodsA qualitative study employing semi-structured interviews was undertaken. Young adults 18-25 years (HbA1c >75mmol/mol (9.0%)), naïve to rtCGM, were provided with rtCGM for 6-months. Interviews (centred on barriers to self-management and experience of rtCGM use) were conducted within 2-weeks of recruitment and at the end. An inductive, thematic analysis of interviews was undertaken.

resultsEight participants (median age (IQR) 23.0 (22.0-24.5) years, 100% non-white ethnicity) were recruited with median HbA1c 94 (88-107) mmol/mol [DCCT 10.8 (10.2-12.1)%.]. All participants used multiple daily insulin injections. Despite low rtCGM wear-time (32.2 (23.1-59.4)%), significant improvements were observed in time in range, but no change in HbA1c. Thematic analysis indicated that high levels of disease burden were reported, with rtCGM-related themes identified: 1) interaction with rtCGM data, 2) feelings of control and trust from using rtCGM, and 3) frustration of technology and alarms. Although participants reported that knowledge of glucose levels on their smartphone was convenient and led to 'greater control', this was countered by alarm-fatigue, technical difficulties and feeling overwhelmed. Three participants prematurely stopped using rtCGM.

conclusionsYoung adults with high-risk hyperglycaemia have complex relationships with rtCGM. rtCGM may have benefits in this high-risk group, but are likely to require additional support and must be determined on a case-by-case basis as associated effort may contribute to feelings of distress and/or burnout. Implementing structured educational, psychosocial, and technical support, alongside alternative care models such as more frequent check-ins, should be considered in order to enhance self-management practices with rtCGM and address technology-related challenges.

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1AdolescentAdultContinuous Glucose MonitoringFemaleGlycated HemoglobinHumansHyperglycemiaInsulinMaleQualitative ResearchYoung AdultBlood GlucoseGlycated HemoglobinInsulin

Identifiers

PMID40315203
PMCPMC12047766

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.