Evidence map›Paper›PMID 40315017›Full record

ArticleJournal of the American Chemical Society2025

Photoswitchable Fluorescent Hydrazone for Super-Resolution Cell Membrane Imaging.

Qingkai Qi, Yunshu Liu, Vedang Puranik, Shefali Patra, Zdenek Svindrych, Xiayi Gong, Ziwei She, Yang Zhang, Ivan Aprahamian

Erratum issuedAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Mechanically Interlocked Indigo Photoswitches.Angewandte Chemie (International ed. in English) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Journal of the American Chemical Society · 2026
    Article
  7. Article
  8. Article
  9. [2.2]Paracyclophane-dicyanorhodanine conjugates as planar chiral molecular photoswitches.Organic chemistry frontiers : an international journal of organic chemistry · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Qingkai QiDepartment of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, United States.
Yunshu LiuMolecular Analytics and Photonics (MAP) Laboratory, Department of Textile Engineering, Chemistry and Science, North Carolina State University, Raleigh, North Carolina 27606, United States.
Vedang PuranikDepartment of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, United States.
Shefali PatraDepartment of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, United States.
Zdenek SvindrychDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire 03755, United States.ORCID 0000-0001-9197-9813
Xiayi GongMolecular Analytics and Photonics (MAP) Laboratory, Department of Textile Engineering, Chemistry and Science, North Carolina State University, Raleigh, North Carolina 27606, United States.
Ziwei SheDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth College, Hanover, New Hampshire 03755, United States.
Yang ZhangMolecular Analytics and Photonics (MAP) Laboratory, Department of Textile Engineering, Chemistry and Science, North Carolina State University, Raleigh, North Carolina 27606, United States.ORCID 0000-0003-1011-3001
Ivan AprahamianDepartment of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, United States.ORCID 0000-0003-2399-8208

Funding

Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MIERKE, DALE F · 2016 to 2025
$25.9M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sue Fenton · 2015 to 2026
$18.3M
Developing Switchable and Functional Fluorophores For Multi-Functional Super-Resolution MicroscopyR35GM155241 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Yang Zhang · 2024 to 2026
$1.1M
Bright and switchable fluorophores for highly multiplexed super-resolution microscopy towards molecular interaction imagingR21GM141675 · NIGMS · NORTHWESTERN UNIVERSITY · PI ZHANG, YANG · 2021 to 2022
$400k
NIEHS NIH HHS P30 ES025128NIGMS NIH HHS P20 GM113132NIGMS NIH HHS R21 GM141675NIGMS NIH HHS R35 GM155241
6 · The paper itself

Abstract

Advancing the field of super-resolution microscopy will require the design and optimization of new molecular probes whose emission can be toggled "ON" and "OFF" using light. Recently, we reported on a hydrazone photochrome (

Indexed as

Cell MembraneFluorescent DyesHydrazonesHumansMolecular StructureOptical ImagingPhotochemical ProcessesFluorescent DyesHydrazones

Identifiers

PMID40315017
PMCPMC12318359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.