Evidence map›Paper›PMID 40314881›Full record

ArticleJournal of nephrology2025

Total kidney volume as a predictor of measured glomerular filtration rate in patients with solid tumors: a prospective cross-sectional analysis.

Regis Otaviano Franca Bezerra, Fernando Louzada Strufaldi, Patricia Perola Dantas, Filipe Andrade, Renato A Caires, Elerson Carlos Costalonga, George Barbério Coura Filho, Luiz A Gil, Marcelo Tatit Sapienza, Giovanni Guido Cerri and 2 more

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Article in Journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Regis Otaviano Franca BezerraServiço de Radiologia do Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Arnaldo, 25, São Paulo, São Paulo, 01246-000, Brazil. regis.bezerra@hsl.org.br.ORCID http://orcid.org/0000-0002-9318-5272
Fernando Louzada StrufaldiServiço de Nefrologia, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9682-3498
Patricia Perola DantasServiço de Radiologia do Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Arnaldo, 25, São Paulo, São Paulo, 01246-000, Brazil.
Filipe AndradeServiço de Radiologia do Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Arnaldo, 25, São Paulo, São Paulo, 01246-000, Brazil.
Renato A CairesServiço de Nefrologia, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Elerson Carlos CostalongaServiço de Nefrologia, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
George Barbério Coura FilhoServiço de Medicina Nuclear, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Luiz A GilLaboratório de Investigação Médica (LIM) 66, Serviço de Geriatria, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Marcelo Tatit SapienzaServiço de Radiologia do Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Arnaldo, 25, São Paulo, São Paulo, 01246-000, Brazil.
Giovanni Guido CerriServiço de Radiologia do Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av. Dr. Arnaldo, 25, São Paulo, São Paulo, 01246-000, Brazil.
Emmanuel A BurdmannLaboratório de Investigação Médica (LIM) 12, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Veronica Torres Costa E SilvaServiço de Nefrologia, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-8211-018X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough previous data demonstrate that total kidney volume (TKV) correlates with measured glomerular filtration rate (mGFR), evidence is however scarce in the oncology setting. The aim of this is study is to evaluate whether adding TKV to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) estimating equations improves the prediction of measured glomerular filtration rate (mGFR) in patients with cancer.

methodsWe evaluated patients with solid tumors between April 2015 and September 2017 who had undergone contrast computed tomography and GFR measurement through the plasma clearance of

resultsWe included 189 patients (median age 58.0 [48.0-65.0] years, 49.2% male). Median mGFR and TKV were 82.7 (66.3-94.5) mL/min and 303.1 (257.7-351.8) cm

conclusionThese results suggest that TKV measurement improves the prediction of mGFR in association with the CKD-EPI equations in patients with solid tumors.

Indexed as

Glomerular Filtration RateKidneyNeoplasmsRenal Insufficiency, ChronicAgedCreatinineCross-Sectional StudiesCystatin CFemaleHumansMaleMiddle AgedOrgan SizePredictive Value of TestsProspective StudiesTomography, X-Ray ComputedCreatinineCystatin CCancerEstimating equationsGlomerular filtration rate

Identifiers

PMID40314881

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.