Evidence map›Paper›PMID 40314859›Full record

SynthesisOral radiology2025

The diagnostic accuracy of cone-beam computed tomography for assessing in vitro osseous alterations of the mandibular condyle: a systematic review and meta-analysis.

Nur Al Amin, Taseef Hasan Farook, Fahmi Oscandar, Mohd Faizal Abdullah, Norliza Binti Ibrahim, Sumaiya Zabin Eusufzai, Johari Yap Abdullah

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Oral radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nur Al AminOral and Maxillofacial Radiology, School of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, 16150, Kota Bharu, Malaysia.
Taseef Hasan FarookAdelaide Dental School, University of Adelaide, Adelaide, SA5000, Australia.
Fahmi OscandarDepartment of Oral and Maxillofacial Radiology, Faculty of Dentistry, Universitas Padjadjaran, 40132, Bandung, Indonesia.
Mohd Faizal AbdullahOral and Maxillofacial Surgery Unit, School of Dental Sciences, Universiti Sains Malaysia. Kubang Kerian, 16150, Kota Bharu, Malaysia.
Norliza Binti IbrahimDepartment of Oral and Maxillofacial Clinical Sciences, Faculty of Dentistry, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.
Sumaiya Zabin EusufzaiSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, 16150, Kota Bharu, Malaysia.
Johari Yap AbdullahCraniofacial Imaging Laboratory, School of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, 16150, Kota Bharu, Kelantan, Malaysia. johariyap@usm.my.ORCID 0000-0002-6147-4192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the diagnostic accuracy of cone-beam computed tomography (CBCT) in detecting simulated bony changes in the mandibular condyle by assessing the sensitivity and specificity.

methodsThis review adhered to PRISMA guidelines. Following predefined eligibility criteria, a search was conducted in four electronic databases in June 2024. The study-level risk of bias was assessed using a diagnostic test accuracy checklist provided by the Joanna Briggs Institute. Pooled estimates of sensitivity and specificity were calculated using a bivariate random-effects model.

resultsAmong 1,803 potentially eligible references, six met the inclusion criteria for qualitative synthesis, and three for meta-analysis. The meta-analysis revealed that the index test, CBCT, had a low pooled sensitivity of 0.54 and a high specificity of 0.93 for detecting simulated defects of the mandibular condyle. Computed tomography exhibited a lower sensitivity of 0.37, but similar specificity of 0.93 like CBCT. Out of the six studies, five were found to have a low risk of bias.

conclusionsCone-beam computed tomography is found to be more accurate than other modalities for detecting condylar bony changes, effectively ruling out false positives, but with a risk of missing true positives. A smaller field of view and voxel size may provide more accurate detection.

Indexed as

Cone-Beam Computed TomographyMandibular CondyleHumansSensitivity and SpecificityDegenerative diseasesDiagnostic accuracy testTemporomandibular disordersTemporomandibular joint

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.