Evidence map›Paper›PMID 40314843›Full record

ArticleActa neurochirurgica2025

MR-guided Laser Interstitial Thermal Therapy mesencephalotomy for medically intractable malignant pain.

Mickael Aubignat, Jean-Marc Constans, Martial Ouendo, Jean-Philippe Arnault, Claire Josse, Christine Desenclos, Michel Lefranc

Abstract readCase Reports
In one paragraph

Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mickael AubignatDepartment of Neurology, Amiens University Hospital, Amiens, France. aubignat.mickael@chu-amiens.fr.
Jean-Marc ConstansDepartment of Radiology, Amiens University Hospital, Amiens, France.
Martial OuendoDepartment of Anesthesiology and Critical Care Medicine, Amiens University Hospital, Amiens, France.
Jean-Philippe ArnaultDepartment of Dermatology, Amiens University Hospital, Amiens, France.
Claire JossePalliative Care Unit, Amiens University Hospital, Amiens, France.
Christine DesenclosDepartment of Neurosurgery, Amiens University Hospital, Amiens, France.
Michel LefrancResearch Unit UR-7516 (CHIMERE) Research Team for Head & Neck, Institute Faire Faces, University of Picardie Jules Verne, Amiens, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereotactic mesencephalotomy is a neurosurgical technique designed to sever spinothalamic pain transmission pathways for medically intractable pain. This report presents the first case of Magnetic Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT) mesencephalotomy for severe malignant pain due to metastatic melanoma. The procedure significantly reduced the patient's pain, with a postoperative visual analog scale (VAS) score decreasing from > 7 to < 3. No adverse effects were observed. The case underscores the potential of MRgLITT mesencephalotomy as a precise, minimally invasive option for pain management in palliative care settings.

Indexed as

Cancer PainIntractable PainLaser TherapyMagnetic Resonance ImagingMelanomaHumansPalliative CareCancerLaser Interstitial Thermal TherapyMelanomaMesencephalotomyMRIPain

Identifiers

PMID40314843
PMCPMC12048455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.