Evidence map›Paper›PMID 40314794›Full record

ArticleEmerging infectious diseases2025

Diagnostic Accuracy of 3 Mpox Lateral Flow Assays for Antigen Detection, Democratic Republic of the Congo and United Kingdom.

Elie Ishara-Nshombo, Anushri Somasundaran, Alessandra Romero-Ramirez, Konstantina Kontogianni, Daniel Mukadi-Bamuleka, Marithé Mukoka-Ntumba, Emile Muhindo-Milonde, Hugues Mirimo-Nguee, Jacob Parkes, Yusra Hussain and 15 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. From neglected to notoriety: a review of Mpox clinical features, virology, epidemiology, treatment and prevention strategies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Review
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Elie Ishara-Nshombo
Anushri Somasundaran
Alessandra Romero-Ramirez
Konstantina Kontogianni
Daniel Mukadi-Bamuleka
Marithé Mukoka-Ntumba
Emile Muhindo-Milonde
Hugues Mirimo-Nguee
Jacob Parkes
Yusra Hussain
Susan Gould
Christopher T Williams
Dominic Wooding
Juvenal Nkeramahame
Mikaela Watson
Hayley E Hardwick
Malcolm G Semple
John Kenneth Baillie
Jake Dunning
Thomas E Fletcher
Thomas Edwards
Devy M Emperador
Hugo Kavunga-Membo
Ana Isabel Cubas-Atienzar
ISARIC 4 and C Investigators

Funding

Wellcome Trust
6 · The paper itself

Abstract

The ongoing outbreaks of mpox highlight the urgent need for a rapid and low-cost diagnostic test to accurately detect and control this emerging disease. We estimated the analytical sensitivity using viral culture of the monkeypox virus clade IIb lineage B1 and clinical diagnostic performance of 3 antigen detection rapid diagnostic tests (Ag-RDT) by using skin swab samples and upper-respiratory swab samples from mpox patients in the Democratic Republic of the Congo and the United Kingdom. The analytical limit of detection was 1.0 × 10

Indexed as

Antigens, ViralMonkeypox virusMpox, MonkeypoxDemocratic Republic of the CongoHumansSensitivity and SpecificityUnited KingdomAntigens, ViralDemocratic Republic of the Congodiagnosticevaluationlateral flow assaylateral flow testLFALFTmonkeypox virusmpoxMPXVOrthopoxvirusPOCTpoint-of-care testPoxviridaerapid diagnostic testRDTsexually transmitted infectionsUnited Kingdom

Identifiers

PMID40314794
PMCPMC12123923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.