Evidence map›Paper›PMID 40314779›Full record

ArticleCurrent microbiology2025

Identification and Biological Characteristics of Rare Pathogen Comamonas kerstersii in the First Case of Gallbladder Puncture Fluid.

Juntong Zhou, Xin Cheng, Liyan Ma, Zhenqi Li, Shuilong Guo

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In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juntong Zhou *Clinical Laboratory Center, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Xin Cheng *Clinical Laboratory Center, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. 15735537628@163.com.
Liyan MaClinical Laboratory Center, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Zhenqi LiDepartment of Laboratory Medicine, Shan County Central Hospital, Heze, 274399, China.
Shuilong GuoDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. slong.guo@163.com.

Funding

the National Key Research and Development Program of China 2021YFC2301004
6 · The paper itself

Abstract

Comamonas kerstersii is an environmental microorganism, and clinical infections caused by this species are rare. In this study, the strain CXZJT123 was isolated from gallbladder puncture fluid and identified using a comprehensive approach including morphological observation, mass spectrometry, biochemical identification, 16S rRNA sequencing, and whole-genome sequencing. The morphological characteristics of CXZJT123 were consistent with the Comamonas. Mass spectrometry initially identified the strain as Comamonas aquatica, while biochemical assays demonstrated key features aligning with the Comamonas genus. Phylogenetic analysis of 16S rRNA sequences placed CXZJT123 in the same clade as C. kerstersii (NR 025530.1). Whole-genome sequencing followed by gene annotation using the Non-Redundant Protein Database (NR) revealed the highest gene homology with C. kerstersii. Further genomic analysis using the Virulence Factors of Pathogenic Bacteria (VFDB) and the Comprehensive Antibiotic Research Database (CARD) identified the presence of virulence genes, including those encoding flagella (flg series) and biofilm formation (pil series), as well as antibiotic resistance genes such as macB, arlR, and evgS. This study presents the first reported isolation of C. kerstersii isolated from gallbladder puncture fluid. The findings contribute valuable insights into the identification, genomic characteristics, and potential pathogenicity of C. kerstersii, providing a useful reference for the diagnosis and management of related infections.

Indexed as

ComamonasGallbladderGram-Negative Bacterial InfectionsAnti-Bacterial AgentsDNA, BacterialGenome, BacterialHumansMaleMiddle AgedPhylogenyRNA, Ribosomal, 16SVirulence FactorsWhole Genome SequencingAnti-Bacterial AgentsDNA, BacterialRNA, Ribosomal, 16SVirulence Factors

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.