Evidence map›Paper›PMID 40314753›Full record

ArticleCurrent microbiology2025

High Yield of Prodigiosin by Serratia marcescens Ka3 Using Additive Huangshui, a Byproduct of Chinese Liquor (Baijiu).

Chuan Wang, Zhongxing Gao, Rui Han, Yaomei Tian, Hongjun Fan, Yuliang Zhang

Abstract read
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In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Breeding ofBiodesign research · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chuan WangCollege of Bioengineering, Sichuan University of Science and Engineering, No.519, Huixing Road, Ziliujing District, Zigong, 643000, China. watpc57944@163.com.
Zhongxing GaoCollege of Bioengineering, Sichuan University of Science and Engineering, No.519, Huixing Road, Ziliujing District, Zigong, 643000, China.
Rui HanCollege of Bioengineering, Sichuan University of Science and Engineering, No.519, Huixing Road, Ziliujing District, Zigong, 643000, China.
Yaomei TianCollege of Bioengineering, Sichuan University of Science and Engineering, No.519, Huixing Road, Ziliujing District, Zigong, 643000, China.
Hongjun FanLuzhou Lunan Wine Co, Ltd. No.160, Shiliang Road, Lingyu Town, Jiangyang District, Luzhou, 646000, China.
Yuliang ZhangLuzhou Lunan Wine Co, Ltd. No.160, Shiliang Road, Lingyu Town, Jiangyang District, Luzhou, 646000, China. 31896009@qq.com.

Funding

Science and Technology Project of Luzhou 2021-SYF-45The Graduate Innovation Fund of Sichuan University of Science and Engineering y2020065The Liquor Making Biological Technology and Application of Key Laboratory of Sichuan Province NJ2018-07The Scientific Research and Innovation Team Program of Sichuan University of Science and Engineering SUSE652B003The Sichuan University of Science & Engineering Innovation and Entrepreneurship Training Program for College Students S202010622073
6 · The paper itself

Abstract

Huangshui, a characteristic byproduct of Chinese liquor production, was first used as an additive to promote the production of prodigiosin with Serratia marcescens Ka3 in a 5 L bioreactor. Based on the prodigiosin levels in the peptone glycerol medium, the yield of prodigiosin reached 48,341 mg/L after adding 1% Huangshui following 60 h of fermentation, which is currently a high yield in bioreactors. The purity of the prodigiosin extracted from the fermentation broth and purified using a microporous filter membrane was 97%. Purified prodigiosin showed significant inhibitory effects on human lung carcinoma A549 cells and human colon adenocarcinoma HT29 cells. It also inhibited the human gastric adenocarcinoma SGC7901 cells, albeit not significantly. The IC

Indexed as

Antineoplastic AgentsProdigiosinSerratia marcescensBioreactorsCell Line, TumorFermentationHumansAntineoplastic AgentsProdigiosin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.