Evidence map›Paper›PMID 40314705›Full record

ArticleOdontology2026

The effect of supplementary methods on root canal cleaning: a study using 3D-printed mandibular molar models.

Estrella Gutiérrez-López, Karla Janeth Córdova-Saucedo, Marco Ramírez-Salomón, Elma Vega-Lizama, P S Ortolani-Seltenerich, Giulia Malvicini, Pedro M Mendez S, Gaya C S Vieira, Alejandro R Pérez

Abstract read
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In one paragraph

Article in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Estrella Gutiérrez-LópezUniversidad Autónoma de Yucatán, Mérida, México.
Karla Janeth Córdova-SaucedoUniversidad Autónoma de Yucatán, Mérida, México.
Marco Ramírez-SalomónUniversidad Autónoma de Yucatán, Mérida, México.
Elma Vega-LizamaUniversidad Autónoma de Yucatán, Mérida, México.
P S Ortolani-SeltenerichDepartment of Dental Pathology and Therapeutics, Faculty of Dentistry, UCAM, Murcia, Spain.
Giulia MalviciniDepartment of Medical Biotechnologies, Unit of Endodontics and Restorative Dentistry, University of Siena, Siena, Italy.
Pedro M Mendez SMember of Surpreendente Research Group, Vila Nova de Gaia, Portugal.
Gaya C S VieiraMember of Surpreendente Research Group, Vila Nova de Gaia, Portugal.
Alejandro R PérezDepartment of Endodontics, Rey Juan Carlos University, Madrid, Spain. aleporon@gmail.com.ORCID http://orcid.org/0000-0002-6925-5939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the cleaning effect of different irrigation and activation techniques in removing residual tissue from the root canal system using 3D-printed resin models based on micro-CT scans of natural teeth. Eleven first mandibular molars with different anatomies were selected, scanned, and replicated six times each, resulting in 66 3D resin models. A hydrogel-based like pulp tissue was injected into the canals to simulate tissue. The samples were divided into six groups: (1) irrigation with saline solution without activation (control), (2) use of positive pressure with NaOCl, (3) sonic activation, (4) wireless PUI activation, (5) conventional wired PUI activation, and (6) XP-Endo finisher agitation. Cleaning efficiency was evaluated by comparing the images before and after irrigation using ImageJ software, quantifying the percentage of remaining tissue. Statistical analysis was performed using one-way ANOVA and post-hoc Tukey's test (p < 0.05). Rinsing with saline solution showed the worst cleaning performance in all canal thirds (p < 0.05). XP-Endo Finisher, Sonic Activation, Wireless PUI, Conventional PUI, and Conventional Syringe Irrigation with NaOCl significantly outperformed saline irrigation. In the apical third, XP-Endo Finisher achieved the lowest residual tissue percentage (5.79%), while saline had the highest (53.82%). No significant differences were found among activation techniques (p > 0.05), not even between the activation techniques and positive pressure irrigation with NaOCl. Sonic Activation and XP-Endo Finisher eliminated tissue in some samples of the middle third. NaOCl irrigation alone effectively dissolves the hydrogel tissue even without activation. Although activation techniques do not provide a consistent statistical advantage, they remain valuable in complex anatomies. Complete tissue removal, particularly in the apical third, remains a challenge. Future research should validate these results in clinical settings and optimize irrigation protocols for improved outcomes.

Indexed as

Models, DentalMolarPrinting, Three-DimensionalRoot Canal IrrigantsRoot Canal PreparationDental Pulp CavityHumansMandibleSodium HypochloriteTherapeutic IrrigationX-Ray MicrotomographyRoot Canal IrrigantsSodium Hypochlorite3D-printed tooth modelsActivation techniquesEndodontic cleaning efficacyResidual tissue removalRoot canal irrigation

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.