Evidence map›Paper›PMID 40314617›Full record

ArticleJournal of chemical information and modeling2025

Evolutionary Dynamics and Functional Differences in Clinically Relevant Pen β-Lactamases from

Jing Gu, Pratul K Agarwal, Robert A Bonomo, Shozeb Haider

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Asymmetric Dynamics Between the Protomers of the σ2 Receptor Homodimer.Journal of chemical information and modeling · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing GuUCL School of Pharmacy, University College London, London WC1N 1AX, U.K.ORCID 0009-0003-1172-9454
Pratul K AgarwalHigh-Performance Computing Center, Oklahoma State University, Stillwater, Oklahoma 74078-1010, United States.ORCID 0000-0002-3848-9492
Robert A BonomoResearch Service, Department of Veterans Affairs Medical Center, Louis Stokes Cleveland, Cleveland, Ohio 44106, United States.ORCID 0000-0002-3299-894X
Shozeb HaiderUCL School of Pharmacy, University College London, London WC1N 1AX, U.K.ORCID 0000-0003-2650-2925

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a global threat, with

Indexed as

beta-LactamasesBurkholderiaEvolution, MolecularMolecular Dynamics SimulationCatalytic DomainMarkov ChainsMutationbeta-Lactamases

Identifiers

PMID40314617
PMCPMC12117567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.