Evidence map›Paper›PMID 40314370›Full record

ReviewJournal of the American Heart Association2025

Cardiac Conduction Disorders Due to Acquired or Genetic Causes in Young Adults: A Review of the Current Literature.

Cristina Balla, Luca Canovi, Marco Zuin, Luca Di Lenno, Maria L Berloni, Beatrice de Carolis, Assunta Di Domenico, Elisabetta Tonet, Francesco Vitali, Michele Malagu and 2 more

Abstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. What Should a Clinical Cardiologist Know About Cardiogenetics?Journal of the American Heart Association · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristina BallaCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0000-0003-2110-8961
Luca CanoviCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.
Marco ZuinCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0000-0002-4559-1292
Luca Di LennoPediatric Cardiology and Adult Congenital Heart Disease Program, Department of Cardio-Thoracic and Vascular Medicine IRCCS Azienda Ospedaliero-Universitaria di Bologna Bologna Italy.
Maria L BerloniCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0009-0002-2774-0853
Beatrice de CarolisCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0009-0009-9397-5977
Assunta Di DomenicoCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0009-0000-3768-3181
Elisabetta TonetCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0000-0003-0257-1272
Francesco VitaliCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0000-0002-0667-7616
Michele MalaguCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0000-0002-1972-9665
Giuseppe BorianiCardiology Division, Department of Biomedical, Metabolic and Neural Sciences University of Modena and Reggio Emilia, Policlinico di Modena Modena Italy.ORCID 0000-0002-9820-4815
Matteo BertiniCardiology Unit Azienda Ospedaliero-Universitaria di Ferrara Cona FE Italy.ORCID 0000-0002-5285-7140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac conduction disorders can manifest in young adults in isolated forms, associated with myocardial diseases or as part of a multiorgan disorder. Underlying causes of cardiac conduction disorders may be genetically determined or acquired. Cardiac conduction disorder in young adults is a complex and often underestimated and underrecognized disease that may need of a multidisciplinary team for the diagnosis, treatment, and long-term management of these patients. Therefore, it is crucial to raise clinicians' awareness of this condition. In this review, we provide a comprehensive update on the cause, diagnosis, and treatment of young adults with cardiac conduction disorders, also suggesting potential strategies to improve the current clinical management of these patients.

Indexed as

Arrhythmias, CardiacCardiac Conduction System DiseaseHeart Conduction SystemAdultElectrocardiographyGenetic Predisposition to DiseaseHumansRisk FactorsYoung Adultatrioventricular blockcardiac conduction disordersgeneticmyocardial diseaseyoung adults

Identifiers

PMID40314370
PMCPMC12184228

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.