Evidence map›Paper›PMID 40314168›Full record

ArticlePsychological medicine2025

Polygenic risk for schizophrenia and subjective well-being in a general population sample.

Oona Serimaa, Liisa Keltikangas-Järvinen, Leo-Pekka Lyytikäinen, Jarmo Hietala, Elina Sormunen, Mika Kähönen, Olli Raitakari, Terho Lehtimäki, Aino Saarinen

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In one paragraph

Article in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Oona SerimaaDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland.
Liisa Keltikangas-JärvinenDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland.
Leo-Pekka LyytikäinenDepartment of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center, Tampere, Finland.
Jarmo HietalaDepartment of Psychiatry, University of Turku and Turku University Hospital, Turku, Finland.
Elina SormunenDepartment of Psychiatry, University of Turku and Turku University Hospital, Turku, Finland.
Mika KähönenDepartment of Clinical Physiology, Tampere University Hospital and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Olli RaitakariResearch Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center, Tampere, Finland.
Aino SaarinenDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland.ORCID 0000-0003-4495-8360

Funding

Emil Aaltosen SäätiöJuho Vainion SäätiöPaavo Nurmen SäätiöSigne ja Ane Gyllenbergin SäätiöSigrid Juséliuksen SäätiöSuomen KulttuurirahastoSydäntutkimussäätiöTampereen TuberkuloosisäätiöYrjö Jahnssonin Säätiö
6 · The paper itself

Abstract

backgroundPrevious evidence has reported associations of a polygenic risk score for schizophrenia (PRS

methodsParticipants (n = 1866) came from the prospective population-based Young Finns Study (YFS). Subjective well-being in adulthood was assessed in terms of life satisfaction, optimism, and self-acceptance (when participants were 20-50 years old). A PRS

resultsThe PRS

conclusionsWhile high PRS

Indexed as

Multifactorial InheritanceOptimismPersonal SatisfactionSchizophreniaAdultFemaleFinlandGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMaleMiddle AgedProspective StudiesRisk FactorsYoung Adultlife satisfactionoptimismpelf-acceptancePRSpsychosis riskpsychotic disorders

Identifiers

PMID40314168
PMCPMC12094622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.