Evidence map›Paper›PMID 40314116›Full record

Observational studyClinical implant dentistry and related research2025

Clinical and Histologic Outcomes of Biologically Oriented Alveolar Ridge Preservation: A Prospective Observational Study.

Antonio Rapani, Leonardo Tonegato, Paolo Savadori, Rebecca Martini, Riccardo Pasquali, Matteo Zotti, Vanessa Nicolin, Federico Berton, Claudio Stacchi

Abstract readObservational Study
In one paragraph

Observational study in Clinical implant dentistry and related research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonio RapaniDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0000-0002-9767-4401
Leonardo TonegatoDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0009-0007-4715-2916
Paolo SavadoriMedical and Dental Department of Morphological Sciences Related to Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy.ORCID https://orcid.org/0000-0001-8606-4694
Rebecca MartiniDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0009-0008-6903-6374
Riccardo PasqualiDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0009-0008-1291-8480
Matteo ZottiDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0009-0000-0200-3895
Vanessa NicolinDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0000-0002-5665-6493
Federico BertonDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0000-0001-6359-9143
Claudio StacchiDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.ORCID https://orcid.org/0000-0003-4017-4980

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to evaluate the efficacy of Biologically oriented Alveolar Ridge Preservation (BARP) in minimizing post-extraction ridge modifications compared with unassisted socket healing.

methodsA prospective controlled observational study was conducted involving 30 patients requiring single-rooted upper premolar extractions. Patients were divided into two groups: the test (15 patients), which underwent a ridge preservation procedure combining absorbable collagen sponge in the middle and apical third of the socket and collagenated xenogeneic bone substitute in the most coronal part (BARP), and the control (15 patients), which healed spontaneously. Soft tissue contour changes after 6 months were analyzed using digital impressions. Moreover, histomorphometric analysis of the regenerated tissue was performed in the test group.

resultsBARP significantly reduced post-extractive mucosal ridge modifications compared to the control group. Mean vertical shrinkage at the mid-buccal part of the edentulous site was 1.61 ± 0.61 mm (BARP) vs. 2.51 ± 0.64 mm (control; t-test, df = 28, p < 0.001), and mean horizontal reduction was 3.37 ± 0.63 mm (BARP) vs. 4.34 ± 0.48 mm (control; t-test, df = 28, p < 0.001). Histomorphometric analysis of the regenerated tissue showed 39.7% ± 9.1% newly formed bone with minimal residual graft material (5.0% ± 5.4%).

conclusionBARP technique effectively minimizes post-extractive soft tissue contour modifications and supports natural bone regeneration, resulting in adequate bone dimensions for implant rehabilitation.

Indexed as

Alveolar Bone LossAlveolar ProcessAlveolar Ridge AugmentationAdultBicuspidBone SubstitutesCollagenFemaleHumansMaleMiddle AgedProspective StudiesTooth ExtractionTooth SocketTreatment OutcomeBone SubstitutesCollagenalveolar ridge preservationbone substitutespost‐extractive ridge modifications

Identifiers

PMID40314116
PMCPMC12046471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.