ArticleSocial cognitive and affective neuroscience2025
The analgesic effect and neural mechanism of spicy food intake.
Article in Social cognitive and affective neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Moderate Food Preferences and Depression with Grey Matter as a Potential Mediator: A Large-Scale Longitudinal Study.Foods (Basel, Switzerland) · 2026Article
- Bidirectional influences and clinical implications of psychological factors and oral health during orthodontic treatment.The Saudi dental journal · 2026Review
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Authors and funding
7 authors.
Funding
Abstract
Although published studies have shown that applying capsaicin to the skin can have an analgesic effect on other parts of the body, the impact of spicy food intake on pain perception and its neurological mechanism remains unclear. Thus, two studies utilizing questionnaires and experiments with event-related potential (ERP) technology were conducted to explore this question. Study 1 recruited 300 adults and found a negative correlation between spicy food cravings and pain perception in daily life. Study 2 involved 45 participants and examined behavioural and ERP responses to pain (including minor pain and moderate pain) stimuli following spicy and control treatments. Results showed that, compared to control treatments, spicy treatments led to shorter reaction times, lower accuracies and pain intensity ratings, less negative emotional responses, smaller N1 and P2 amplitudes, and shorter N1 and P2 latencies, especially for minor-pain stimuli. These findings indicate that spicy food intake may have an analgesic effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.